Low-dose niacin supplementation modulates GPR109A, niacin index and ameliorates Parkinson's disease symptoms without side effects.

Author: BradleyEric, ChongRaymond, MorganJohn C, WakadeChandramohan

Paper Details 
Original Abstract of the Article :
A 65-year-old male, Parkinson's disease patient, was evaluated for GPR109A expression, niacin index, UPDRS scale, handwriting test, and quality of sleep with and without niacin treatment. The evaluation was repeated 3 months after niacin was stopped. Niacin modulated the abovementioned parameters an...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527813/

データ提供:米国国立医学図書館(NLM)

A Glimpse into the Effects of Niacin on Parkinson's Disease

The field of Parkinson's disease research is always searching for new ways to manage the condition. This study explores the potential of low-dose niacin supplementation as a treatment option. The researchers utilized a unique approach by observing a single Parkinson's disease patient, monitoring their GPR109A expression, niacin index, and various clinical parameters, both with and without niacin treatment. Their observations indicated that niacin supplementation modulated these parameters and showed a positive impact on the patient's condition, without any apparent adverse effects. This research provides intriguing insights into the potential benefits of niacin for Parkinson's disease management.

Promising Results for Parkinson's Disease

This fascinating case study demonstrates that low-dose niacin supplementation may hold promise as a therapeutic option for Parkinson's disease. The observed improvements in GPR109A expression, niacin index, and clinical parameters, including the UPDRS scale, handwriting test, and quality of sleep, suggest that niacin might have a positive impact on the disease's progression. The lack of reported side effects makes niacin an even more appealing prospect for future investigation.

Niacin - A Potential Ally in Managing Parkinson's Disease

This study, while limited by its single-patient design, hints at the potential of niacin as a novel treatment for Parkinson's disease. If further studies corroborate these findings, niacin could offer a promising alternative or complementary approach for managing the condition. It's important to note that this research is still in its early stages, and more extensive studies are necessary to confirm these findings and establish the safety and efficacy of niacin in a broader population of Parkinson's disease patients.

Dr.Camel's Conclusion

Just like a camel traversing a vast desert, scientists continue to explore new pathways in Parkinson's disease research. This study suggests that niacin might be a hidden oasis in the desert of treatment options. However, we need to tread cautiously and conduct further research to confirm the effectiveness of this potential treatment. Remember, stay hydrated and keep an open mind as we embark on this journey of scientific discovery!

Date :
  1. Date Completed 2015-08-14
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

26273459

DOI: Digital Object Identifier

PMC4527813

Related Literature

SNS
PICO Info
in preparation
Languages

English

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