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Glasgow Antipsychotic Side-effects Scale for Clozapine - Development and validation of a clozapine-specific side-effects scale.

Author: ClarkeMary, DrakeRichard J, FeetamCelia, GaughranFiona, HaddadPeter M, HynesCaroline, KeatingDolores, KinsellaAnthony, MadiganKevin, MaidmentIan, McWilliamsStephen, TaylorMark

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Validation StudyResearch to assess the validity and reliability of new measurement methods or diagnostic tests.

Overview

A study of 110 clozapine outpatients found that the GASS-C (Glasgow Antipsychotic Side-effects Scale for Clozapine) is a valid and reliable clinical tool to assess the subjectively unpleasant side-effects of clozapine.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: The authors developed and validated a clozapine-specific side-effects scale capable of eliciting the subjectively unpleasant side-effects of clozapine. METHODS: Questions from the original Glasgow Antipsychotic Side-effects Scale (GASS) were compared to a list of the most commonly report...See full text at original site
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引用元：
https://doi.org/10.1016/j.schres.2015.07.052

データ提供：米国国立医学図書館（NLM）

The Glasgow Antipsychotic Side-effects Scale for Clozapine: A New Tool for Assessing Clozapine Side-Effects

The use of [clozapine], a [second-generation antipsychotic], is often associated with [subjectively unpleasant side-effects]. This study developed and validated a [clozapine-specific side-effects scale] to facilitate the assessment of these side-effects. The authors drew upon the [Glasgow Antipsychotic Side-effects Scale (GASS)] and incorporated questions specific to [clozapine]. The new scale, [GASS for Clozapine (GASS-C)], demonstrated [construct validity and strong test-retest reliability]. This development provides a valuable tool for clinicians to systematically assess and manage the side-effects of [clozapine] therapy.

GASS-C: A Valuable Tool for Managing Clozapine Side-Effects

The development of [GASS-C] provides clinicians with a valuable tool to systematically assess the [subjectively unpleasant side-effects] of [clozapine] therapy. This can help to improve patient care by facilitating early detection and management of these side effects, ultimately enhancing the quality of life for patients receiving [clozapine] treatment.

Navigating the Desert of Antipsychotic Therapy: GASS-C Offers a Map

The desert of [antipsychotic therapy] can be a challenging landscape for patients and clinicians alike, with potential side effects adding complexity to the treatment journey. This study offers a valuable resource in the form of [GASS-C], a [clozapine-specific side-effects scale]. It's like finding a detailed map through the desert, providing guidance for clinicians to navigate the potential side effects and manage them effectively.

Dr.Camel's Conclusion

The development of [GASS-C] is a significant step forward in the management of [clozapine] side-effects. It's like finding a well-stocked oasis in the desert of antipsychotic therapy, providing tools and resources for clinicians to address these challenging side effects and improve patient outcomes.

Date :
  1. Date Completed 2016-07-06
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

26276305

DOI: Digital Object Identifier

10.1016/j.schres.2015.07.052

Related Literature

Article Analysis
・Side Effects of clozapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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