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Comparison of subcutaneous injections of terbutaline, salbutamol and adrenaline in acute asthmatic attacks in children.

Author: PhanichyakarnP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Terbutaline, adrenaline, and salbutamol, bronchodilator drugs, were compared for their effects on bronchodilation and cardiovascular function in a randomized study. Terbutaline showed the most potent bronchodilation, while all drugs caused increases in heart rate, systolic blood pressure, and respiratory rate.
Paper Details　
Original Abstract of the Article :
Bronchodilating and cardiovascular effects of subcutaneously administered terbutaline, adrenaline 0.01 mg/kg and salbutamol 0.007 mg/kg were compared in a randomized single-blind manner. All drugs produced bronchodilation within 2 minutes and maintained it for 4 hours with terbutaline and adrenaline...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2628537

データ提供：米国国立医学図書館（NLM）

Comparing Bronchodilators for Acute Asthma Attacks in Children

This study delves into the realm of pediatric respiratory medicine, focusing on the effectiveness of different bronchodilators for treating acute asthma attacks in children. The researchers compared the effects of terbutaline, adrenaline, and salbutamol administered subcutaneously in a randomized, single-blind manner.

Terbutaline: The Most Effective Bronchodilator

All three bronchodilators produced significant bronchodilation within two minutes, but terbutaline emerged as the most effective in terms of both onset and duration of action. While all drugs caused an increase in heart rate, terbutaline also led to the highest increase in systolic blood pressure.

Choosing the Right Bronchodilator for Young Patients

The study highlights the need for careful consideration when selecting a bronchodilator for children with acute asthma. The choice should be based on factors such as the severity of the asthma attack, the patient's age, and their overall health status. It's crucial to use these medications safely and effectively to alleviate asthma symptoms and improve a child's well-being.

Dr. Camel's Conclusion

This research emphasizes the importance of individualized treatment for children with asthma. Just as a camel adapts its stride to the shifting sands of the desert, we must adjust our approach to treating young patients with acute asthma attacks to ensure their optimal health and well-being.

Date :
  1. Date Completed 1990-04-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2628537

DOI: Digital Object Identifier

2628537

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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