Comparative in vitro activity of oral antimicrobial agents against Enterobacteriaceae from patients with community-acquired urinary tract infections in three European countries.

Author: BatistaN, BesardV, BiedenbachD J, CantónR, García-CastilloM, Kalka-MollW, KreskenM, Körber-IrrgangB, PascualA, SchwarzR, SeifertH, Van MeenselB, WisplinghoffH

Paper Details 
Original Abstract of the Article :
Enterobacteriaceae causing community-acquired urinary tract infections were examined in selected outpatient clinics and hospitals in Belgium, Germany and Spain using EUCAST breakpoints for susceptibility. A total of 1190 isolates were collected. Escherichia coli isolates were resistant to amoxicilli...See full text at original site
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引用元:
https://doi.org/10.1016/j.cmi.2015.08.019

データ提供:米国国立医学図書館(NLM)

A Microbial Oasis: Antimicrobial Resistance in Urinary Tract Infections

Urinary tract infections (UTIs), a common affliction, are like a persistent desert wind, bringing discomfort and potential complications. This study examines the prevalence of antimicrobial resistance among Enterobacteriaceae, a group of bacteria commonly associated with UTIs, in three European countries. The researchers, like scientists mapping a microbial desert, analyzed a large collection of bacterial isolates, meticulously evaluating their susceptibility to various antimicrobial agents. Their findings, like a detailed map of the microbial landscape, provide valuable insights into the evolving nature of antimicrobial resistance and the challenges it poses to effective treatment.

A Shifting Landscape: The Rise of Antimicrobial Resistance

The study reveals a concerning trend of increasing antimicrobial resistance among Enterobacteriaceae, particularly to commonly used antibiotics such as amoxicillin-clavulanic acid, ciprofloxacin, and trimethoprim-sulfamethoxazole. This finding is like a warning sign in the desert, alerting us to the need for vigilance in managing antimicrobial resistance. The researchers identify fosfomycin and nitrofurantoin as potential alternatives for treating these infections, providing a glimmer of hope in the face of escalating resistance.

Navigating the Desert of Antimicrobial Resistance

This research underscores the importance of responsible antibiotic use and the need for ongoing surveillance to track the emergence and spread of antimicrobial resistance. It also highlights the need for continued research and development of new antimicrobial agents to combat the growing threat of drug-resistant infections. This study, like a compass in the desert, provides valuable direction for navigating the complex landscape of antimicrobial resistance, ensuring the efficacy of treatments and protecting public health.

Dr. Camel's Conclusion

This study takes us on an expedition into the microbial desert of urinary tract infections, unveiling the challenges posed by antimicrobial resistance. The research highlights the need for a multi-pronged approach to combatting this threat, including responsible antibiotic use, ongoing surveillance, and continued research to develop new solutions. It reminds us that the fight against drug-resistant infections is an ongoing journey, requiring vigilance and innovation to protect public health.
Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

26321667

DOI: Digital Object Identifier

10.1016/j.cmi.2015.08.019

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