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A comparison of the effectiveness of risperidone, haloperidol and flupentixol long-acting injections in patients with schizophrenia--A nationwide study.

Author: ChangWei Hung, ChenKao Chin, ChenPo See, ChiMei Hung, HsiaoChih Yin, Hui LeeI, LeeLan-Ting, YangYen Kuang, YuHsaing-Yuan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Risperidone long-acting injection (RLAI) is not superior to haloperidol or flupentixol long-acting injections in terms of effectiveness, but it might have fewer adverse effects.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Risperidone long-acting injection (RLAI), the first licensed, long-acting second-generation antipsychotic (SGA), has not yet been studied in terms of its effectiveness compared with first-generation antipsychotic (FGA) LAIs. METHODS: The differences in the effectiveness of RLAI and two ...See full text at original site
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引用元：
https://doi.org/10.1016/j.schres.2015.09.006

データ提供：米国国立医学図書館（NLM）

Risperidone, Haloperidol, and Flupentixol: Navigating the Sands of Schizophrenia Treatment

The search for effective treatments for schizophrenia continues, with a variety of medications vying for a place in the therapeutic landscape. This nationwide study compared the effectiveness of risperidone long-acting injection (RLAI) with two first-generation antipsychotic (FGA) long-acting injections, haloperidol and flupentixol. The researchers assessed their effectiveness in terms of medical care utilization and relapse prevention.

Comparing Therapeutic Approaches in the Desert of Schizophrenia

The study found that haloperidol injection was associated with a lower number of relapses compared to the pre-LAI period, while RLAI was associated with higher rates of acute admissions, relapses, and longer hospital stays. However, RLAI was associated with lower utilization of anticholinergic agents.

Navigating the Treatment Options for Schizophrenia

The research provides valuable insights for clinicians seeking to optimize the treatment of schizophrenia. It highlights the importance of considering the specific needs of each patient and choosing the most appropriate medication based on their individual risk factors and preferences.

Dr.Camel's Conclusion

The search for effective treatments for schizophrenia is an ongoing journey, much like a traveler traversing a vast and unforgiving desert. This study offers a valuable comparison of different therapeutic approaches, providing clinicians with valuable information to guide their treatment decisions.

Date :
  1. Date Completed 2016-09-28
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

26395153

DOI: Digital Object Identifier

10.1016/j.schres.2015.09.006

Related Literature

Article Analysis
・Effects of haloperidol injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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