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The Role of Systemic Retinoids in the Treatment of Cutaneous T-Cell Lymphoma.

Author: HuenAuris O, KimEllen J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Retinoids are vitamin A analogs with significant activity in hematologic malignancies, particularly cutaneous T-cell lymphoma. Systemic retinoids can be used as monotherapy or in combination with other agents. Side effects include teratogenicity, dyslipidemias, and hypothyroidism.
Paper Details　
Original Abstract of the Article :
Retinoids are natural and synthetic vitamin A analogs with effects on cell proliferation, differentiation, and apoptosis. They have significant activity in hematologic malignancies and have been studied extensively in cutaneous T-cell lymphoma. Retinoids bind to nuclear receptors and exert their eff...See full text at original site
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引用元：
https://doi.org/10.1016/j.det.2015.05.007

データ提供：米国国立医学図書館（NLM）

Cutaneous T-Cell Lymphoma: Finding a Path Through the Desert of Cancer

Cutaneous T-cell lymphoma (CTCL), a type of cancer that affects the skin, can feel like navigating a desolate desert of uncertainty and discomfort. This research examines the role of systemic retinoids in treating CTCL, a class of drugs derived from vitamin A. The study provides a comprehensive review of existing research exploring the use of retinoids as both monotherapy and in combination with other agents against CTCL.

Retinoids: A Potential Oasis in the Desert of CTCL

The study explores the potential of retinoids as a therapeutic tool for CTCL, offering hope for those facing this challenging diagnosis. Retinoids, like a refreshing oasis in the desert, have shown promising activity against CTCL, potentially slowing the progression of the disease and improving patient outcomes. This research highlights the potential of retinoids as a valuable therapeutic option for managing CTCL.

Navigating the Desert of Cancer Treatment

This research reminds us that the journey through cancer treatment can be challenging, much like traversing a vast and unforgiving desert. It underscores the importance of collaborating with healthcare professionals to explore all available treatment options and find the most effective path for managing the disease. By working together, individuals can find a more manageable path through the desert of cancer treatment.

Dr.Camel's Conclusion

Navigating the desert of CTCL can be a daunting experience, but retinoids offer a glimmer of hope, like an oasis in the sand. This research highlights the potential of these vitamin A derivatives as a valuable therapeutic tool for managing this challenging disease. It emphasizes the importance of seeking guidance from healthcare professionals and working together to find the most effective path for managing CTCL and improving patient outcomes.

Date :
  1. Date Completed 2016-07-13
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26433844

DOI: Digital Object Identifier

10.1016/j.det.2015.05.007

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Languages

English

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