Loss of Afferent Vestibular Input Produces Central Adaptation and Increased Gain of Vestibular Prosthetic Stimulation.

Author: KanekoChris R S, LingLeo, NieKaibao, NowackAmy, PhillipsChristopher, PhillipsJames O, RubinsteinJay T, ShepherdSarah J

Paper Details 
Original Abstract of the Article :
Implanted vestibular neurostimulators are effective in driving slow phase eye movements in monkeys and humans. Furthermore, increases in slow phase velocity and electrically evoked compound action potential (vECAP) amplitudes occur with increasing current amplitude of electrical stimulation. In inta...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722019/

データ提供:米国国立医学図書館(NLM)

Vestibular Neurostimulators: Adapting to the Desert of Sensory Loss

The treatment of [vestibular disorders] is constantly evolving, with [implanted vestibular neurostimulators] offering a promising new approach. This study investigates the [central adaptation] that occurs in response to [loss of afferent vestibular input] and the subsequent [increased gain] of [vestibular prosthetic stimulation]. The researchers conducted experiments in [monkeys] with [long-standing stably functioning vestibular neurostimulators] to understand the adaptive mechanisms involved in [vestibular rehabilitation].

A New Oasis: Central Adaptation to Vestibular Loss

The study demonstrates that [loss of vestibular afferent activity] triggers [central adaptive changes] in the [vestibular system], leading to an [increased gain] of [vestibular prosthetic stimulation]. This finding suggests that the brain can adapt to [sensory loss] and optimize the effectiveness of [vestibular neurostimulators]. This adaptation is critical for achieving optimal [vestibular rehabilitation] outcomes.

Navigating the Desert of Vestibular Disorders: Adapting to Change

This research underscores the remarkable plasticity of the [brain] in adapting to [sensory loss]. It suggests that [vestibular rehabilitation] is a dynamic process that involves both [peripheral stimulation] and [central adaptation]. This understanding is essential for developing [effective treatment strategies] for [vestibular disorders].

Dr.Camel's Conclusion

The desert of [vestibular disorders] can be a disorienting and challenging place. This study demonstrates the brain's ability to adapt to [sensory loss], creating new pathways to regain balance and function. This remarkable adaptation underscores the potential of [vestibular neurostimulators] to provide a new oasis of hope for individuals with [vestibular disorders].

Date :
  1. Date Completed 2016-10-21
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26438271

DOI: Digital Object Identifier

PMC4722019

Related Literature

SNS
PICO Info
in preparation
Languages

English

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