Esomeprazole and rabeprazole did not reduce antiplatelet effects of aspirin/clopidogrel dual therapy in patients undergoing percutaneous coronary intervention: a prospective, randomized, case-control study.

Author: ChengKang, GuoWen-Yi, LiuLi-Peng, SiRui, WangYan, YuanMing

Paper Details 
Original Abstract of the Article :
Controversy has been prompted based on drug interaction between proton pump inhibitors (PPIs) and aspirin/clopidogrel leading to weakened effects. However, whether such interaction was drug-specific or class effect remains controversial. This study predicted the impact of esomeprazole and rabeprazol...See full text at original site
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引用元:
https://doi.org/10.1517/14656566.2016.1110145

データ提供:米国国立医学図書館(NLM)

PPIs and Antiplatelet Therapy: A Complex Interaction in the Cardiovascular Realm

The world of cardiovascular health is filled with intricate interactions between various medications. This study delves into the complex relationship between proton pump inhibitors (PPIs) and antiplatelet therapy, specifically focusing on the potential impact of esomeprazole and rabeprazole on aspirin/clopidogrel dual therapy.

The study investigated the effects of esomeprazole and rabeprazole on the antiplatelet effects of aspirin/clopidogrel dual therapy in patients undergoing percutaneous coronary intervention. The results showed that esomeprazole and rabeprazole did not reduce the antiplatelet effects of aspirin/clopidogrel, addressing concerns about potential drug interactions in this context.

Navigating the Cardiovascular Desert: Understanding Drug Interactions

This research provides crucial insights into the potential interactions between PPIs and antiplatelet therapy, offering valuable information for healthcare professionals managing cardiovascular patients. The study's findings help clarify the complex relationship between these medications, guiding clinicians in making informed decisions about patient care.

Maintaining Cardiovascular Health: Managing Medications Wisely

The study emphasizes the importance of managing medications wisely in cardiovascular patients. Understanding the potential interactions between different medications is crucial for ensuring patient safety and optimizing treatment outcomes.

Dr.Camel's Conclusion

This research illuminates the complex world of drug interactions, particularly in the realm of cardiovascular health. It's like navigating a vast desert, carefully considering the potential impact of each medication on the overall treatment plan. The study's findings offer valuable guidance for clinicians, ensuring that patients receive the best possible care in managing their cardiovascular health.

Date :
  1. Date Completed 2016-06-27
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26549402

DOI: Digital Object Identifier

10.1517/14656566.2016.1110145

Related Literature

SNS
PICO Info
in preparation
Languages

English

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