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Niacin and Chronic Kidney Disease.

Author: MasudaMasashi, MiyamotoKen-ichi, SegawaHiroko, TakedaEiji, TaketaniYutaka, TatsumiSawako, YamamotoHironori, Yamanaka-OkumuraHisami

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Chronic kidney disease (CKD) patients are at risk for cardiovascular disease (CVD). CKD-mineral and bone disorder (CKD-MBD) contributes to CVD, and hyperphosphatemia is a key risk factor. Phosphate binders, commonly used to manage hyperphosphatemia, have undesirable side effects. This study explores the potential benefits of nicotinamide, which can inhibit intestinal phosphate transport, for managing both hyperphosphatemia and dyslipidemia in CKD patients, ultimately reducing CVD risk.
Paper Details　
Original Abstract of the Article :
Chronic kidney disease (CKD) is an increasing problem worldwide. The number of end-stage renal disease patients requiring treatment by dialysis is estimated to be increasing by 10,000 patients per year in Japan. Furthermore, an estimated 13 million people are living with CKD in Japan. Various compli...See full text at original site
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引用元：
https://doi.org/10.3177/jnsv.61.S173

データ提供：米国国立医学図書館（NLM）

Niacin: A Potential Treatment for Chronic Kidney Disease

Chronic kidney disease (CKD) is a serious global health concern, often leading to cardiovascular disease (CVD). This study explores the potential therapeutic benefits of niacin and related compounds in managing CKD and reducing the risk of CVD.

The study focuses on the role of niacin in managing hyperphosphatemia, a common complication of CKD. Niacin, in the form of nicotinamide, can inhibit intestinal phosphate transport, potentially reducing serum phosphate levels. The study also highlights the potential benefits of niacin in managing dyslipidemia, a common risk factor for CVD in CKD patients.

Niacin: A Multi-faceted Approach to CKD Management

Imagine a camel caravan traversing a challenging desert environment. Niacin, like a resourceful traveler, addresses multiple needs simultaneously. It helps to manage hyperphosphatemia, a threat to the camel's health, and dyslipidemia, a risk factor for navigating the treacherous terrain.

Hope for CKD Patients

The study suggests that niacin and related compounds may offer a valuable treatment option for CKD patients, potentially reducing the risk of CVD and improving overall health outcomes. Further research is needed to confirm its efficacy and optimize its use in CKD management.

Dr.Camel's Conclusion

Niacin, like a resourceful traveler, offers a multifaceted approach to managing the challenges of chronic kidney disease, potentially improving the health and well-being of those navigating this difficult landscape.

Date :
  1. Date Completed 2016-08-22
  2. Date Revised 2015-11-25
Further Info :

Pubmed ID

26598845

DOI: Digital Object Identifier

10.3177/jnsv.61.S173

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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