Re-re-treatment of hepatitis C virus: Eight patients who relapsed twice after direct-acting-antiviral drugs.

Author: BichoupanKian, BranchAndrea D, ChekuriSweta, DieterichDouglas, HartmanJoshua, HartyAlyson, PatelNeal, PerumalswamiPonni

Paper Details 
Original Abstract of the Article :
AIM: To determine risk factors associated with hepatitis C virus (HCV) treatment failure after direct acting antivirals in patients with complex treatment histories. METHODS: All HCV mono-infected patients who received treatment at our institution were queried. Analysis was restricted to patients w...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649126/

データ提供:米国国立医学図書館(NLM)

Hepatitis C Virus: Challenges of Re-treatment After Direct-Acting Antiviral Drugs

This study investigates the [Risk factors associated with hepatitis C virus (HCV) treatment failure] in patients who [Relapsed twice after direct-acting antiviral drugs]. The study uses [Retrospective analysis of patient data] to identify [Possible causes of re-treatment failure]. The authors discovered that [Patients with liver cirrhosis and high-titer genotype 1a HCV are at higher risk of treatment failure with simeprevir and sofosbuvir] even with the addition of ribavirin. This finding is important because [It highlights the complexity of HCV treatment and the need for individualized treatment strategies].

The Complexity of HCV Treatment

The study's findings suggest that [Treating HCV in patients with complex treatment histories can be challenging, and a 12-week regimen may be insufficient for certain patients].

Navigating the Treatment of Hepatitis C

This research underscores the importance of consulting a qualified healthcare professional for personalized HCV treatment plans. Just as a camel adapts to the harsh desert conditions, we must also adapt to the unique challenges of HCV and seek appropriate medical care.

Dr. Camel's Conclusion

This study is a reminder that the fight against HCV is an ongoing battle. It highlights the need for continued research to develop more effective treatment options, especially for patients with complex medical histories. It's a reminder that we must approach medical challenges with perseverance and a commitment to finding solutions for all.
Date :
  1. Date Completed 2016-11-07
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26604650

DOI: Digital Object Identifier

PMC4649126

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Languages

English

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