Paper Details

  1. Home
  2. Paper Details

Zwitterionic nanoparticles constructed from bioreducible RAFT-ROP double head agent for shell shedding triggered intracellular drug delivery.

Author: DongAnjie, HuangPingsheng, KongDeling, LiuJianfeng, LiuJinjian, WangWeiwei, ZhangYumin, ZhaoFuli

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Nanomedicines for cancer therapy often face challenges with drug delivery. This study developed novel bioreducible nanoparticles that overcome these barriers by releasing drugs rapidly and effectively within cells. The nanoparticles demonstrate superior antitumor activity and lower toxicity compared to free drugs in mice.
Paper Details　
Original Abstract of the Article :
Nanomedicines have emerged as indispensable platforms for cancer theranostics, however, the therapeutic outcomes were often compromised not only by the multiple biological barriers during the itinerary from the initial injection site to the intracellular action site but also the insufficient drug re...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.actbio.2015.11.038

データ提供：米国国立医学図書館（NLM）

Nanoparticles: Smart Delivery Systems for Cancer Treatment

Cancer, a relentless enemy in the war against disease, can be like a vast and unforgiving desert landscape. This study explores a new approach to cancer treatment, using nanoparticles as smart delivery systems for drugs. The researchers developed a novel nanoparticle design that allows for controlled release of drugs within the body. Imagine these nanoparticles like tiny camels carrying precious cargo of drugs, navigating the complex terrain of the body to deliver their payload directly to cancer cells. This study is like a groundbreaking discovery in the desert, paving the way for more effective and targeted cancer therapies.

Smart Nanoparticles: Navigating the Desert of Cancer

The study's findings highlight the potential of these innovative nanoparticles to enhance drug delivery and effectiveness. This research, like a well-equipped caravan, provides a new strategy for navigating the complex landscape of cancer treatment.

A New Frontier in Cancer Treatment

This study provides a glimpse into the future of cancer treatment, showcasing the power of nanotechnology to deliver drugs more effectively and precisely. It's a reminder that innovation and scientific breakthroughs are crucial for conquering this challenging disease.

Dr. Camel's Conclusion

The desert of cancer can be a harsh and unforgiving landscape, but this study offers a beacon of hope. The development of these smart nanoparticles, like a well-planned expedition, offers a new path for delivering drugs more effectively and targeting cancer cells with greater precision. This research represents a promising step forward in the fight against this deadly disease.

Date :
  1. Date Completed 2017-10-13
  2. Date Revised 2017-11-17
Further Info :

Pubmed ID

26607767

DOI: Digital Object Identifier

10.1016/j.actbio.2015.11.038

Related Literature

Article Analysis
・Side Effects of betaine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.