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A Randomized Controlled Exploratory Pilot Study to Evaluate the Effect of Rotigotine Transdermal Patch on Parkinson's Disease-Associated Chronic Pain.
Author: AsgharnejadMahnaz, BauerLars, ChaudhuriK Ray, DohinElisabeth, NiliusSigrid, RascolOlivier, SurmannErwin, ZesiewiczTheresa
Original Abstract of the Article :
Pain is a troublesome nonmotor symptom of Parkinson's disease (PD). This double-blind exploratory pilot study (NCT01744496) was the first to specifically investigate the effect of a dopamine agonist on PD-associated pain as primary outcome. Patients with advanced PD (ie, receiving levodopa) and at l...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/jcph.678
データ提供:米国国立医学図書館(NLM)
Rotigotine: A Potential Pain Reliever for Parkinson's Disease?
Parkinson's disease (PD), a neurodegenerative disorder, often comes with debilitating nonmotor symptoms, including chronic pain. This research investigates the potential of rotigotine, a dopamine agonist, to alleviate PD-associated chronic pain. The study, a double-blind exploratory pilot study, involved patients with advanced PD experiencing chronic pain. Patients were randomly assigned to receive either rotigotine or placebo for 12 weeks.
Rotigotine: A Potential Hope for PD-Associated Chronic Pain
The study found that rotigotine appeared to improve pain severity in patients with PD-associated chronic pain, with a numerical improvement in pain scores compared to placebo. While the study was exploratory and requires further confirmation in larger-scale studies, the findings suggest that rotigotine may offer a potential therapeutic option for managing PD-associated chronic pain.
Managing PD-Associated Pain: Exploring Novel Approaches
This research provides a promising lead for exploring new approaches to managing PD-associated chronic pain. Rotigotine, a dopamine agonist already used for treating PD symptoms, may offer a potential therapeutic option for addressing this debilitating nonmotor symptom. However, further research is needed to confirm these findings and assess the long-term efficacy and safety of rotigotine for managing PD-associated pain. Remember, just as a camel adapts to the desert's changing conditions, we must remain open to exploring novel approaches for addressing complex health challenges.
Dr. Camel's Conclusion
This research offers a glimmer of hope for individuals with PD-associated chronic pain. Rotigotine, a dopamine agonist, may offer a potential therapeutic option for alleviating pain. However, further research is needed to confirm these findings and assess the long-term efficacy and safety of rotigotine for managing this debilitating symptom. Remember, just as a camel navigates the desert with resilience and adaptability, we must remain committed to exploring new avenues for treating complex medical conditions.
Date :
- Date Completed 2017-08-15
- Date Revised 2022-03-21
Further Info :
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