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Randomized Controlled Trial of Darbepoetin α Versus Continuous Erythropoietin Receptor Activator Injected Subcutaneously Once Every Four Weeks in Patients with Chronic Kidney Disease at the Pre-Dialysis Stage.
Author: AbeMasanori, FurukawaTetsuya, MaruyamaNoriaki, MaruyamaTakashi, OikawaOsamu, OkadaKazuyoshi, TeiRitsukou
Original Abstract of the Article :
Continuous erythropoietin receptor activator (CERA) seems to maintain a stable hemoglobin (Hb) level because its half-life is longer than darbepoetin α (DA). Twenty chronic kidney disease (CKD) patients at the pre-dialysis stage who had been administered DA for over 24 weeks were randomly assigned t...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691171/
データ提供:米国国立医学図書館(NLM)
Darbepoetin α vs. Continuous Erythropoietin Receptor Activator: A Race for Hemoglobin Levels
This study compares the effectiveness of two medications, darbepoetin α (DA) and continuous erythropoietin receptor activator (CERA), in managing hemoglobin (Hb) levels in patients with chronic kidney disease (CKD) at the pre-dialysis stage. The study investigates the impact of these medications on Hb levels, reticulocyte count, and other clinical markers. The findings suggest that both DA and CERA, when administered once every four weeks, show comparable effectiveness in achieving target Hb levels.
A Tale of Two Medications: A Neck-and-Neck Race for Hemoglobin
This study reveals that both DA and CERA can be effective in maintaining stable Hb levels in CKD patients. It’s like a race across a desert – both camels are strong and capable of reaching the destination, but they may have different strengths and strategies. This research suggests that the choice between DA and CERA may be influenced by individual patient factors and preferences.
Navigating the CKD Desert: Optimizing Treatment Strategies
This study highlights the importance of tailoring treatment strategies to the specific needs of CKD patients. It suggests that both DA and CERA can be valuable tools in managing Hb levels, emphasizing the importance of individualized care and monitoring. It’s like navigating a desert – understanding the unique challenges of each individual and having the right tools can make all the difference.
Dr.Camel's Conclusion
This study underscores the importance of ongoing research in optimizing treatment strategies for CKD patients. The findings suggest that both DA and CERA can play a significant role in managing Hb levels, but further studies are needed to understand the long-term impact of these medications. It’s like a journey across a desert – we need to constantly refine our strategies and adapt to the changing landscape to achieve the best possible outcomes.
Date :
- Date Completed 2016-10-05
- Date Revised 2018-12-02
Further Info :
Related Literature
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