Salbutamol in the 1980s. A reappraisal of its clinical efficacy.

Author: ClissoldS P, PriceA H

Paper Details 
Original Abstract of the Article :
Salbutamol (albuterol) is a beta 2-selective adrenoceptor agonist which accounts for its pronounced bronchodilatory, cardiac, uterine and metabolic effects. During the intervening years since salbutamol was first reviewed in the Journal (1971), it has become extensively used in the treatment of reve...See full text at original site
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引用元:
https://doi.org/10.2165/00003495-198938010-00004

データ提供:米国国立医学図書館(NLM)

Salbutamol: A Bronchodilator with a Long History

The world of respiratory medicine is constantly evolving, but some medications remain steadfast in their effectiveness. This research dives into the realm of bronchodilators, specifically focusing on Salbutamol (albuterol), a beta 2-selective adrenoceptor agonist. The authors utilized a comprehensive literature review to assess the efficacy and safety of Salbutamol in treating reversible obstructive airways disease, particularly asthma, over the past two decades. Their findings confirm Salbutamol's effectiveness as a first-line therapy, highlighting its rapid bronchodilation action, typically relieving symptoms within minutes. They also shed light on the nuances of its administration, indicating that inhaled Salbutamol is generally preferred, while oral Salbutamol provides a viable alternative for patients who struggle with inhaler coordination. The study further underscores the safety profile of Salbutamol, indicating that side effects are usually predictable and dose-dependent, with the most frequent being tremor, tachycardia, and hypokalaemia.

Salbutamol: A Timeless Solution for Respiratory Distress

The results of this study highlight the enduring value of Salbutamol in managing reversible obstructive airways disease, specifically asthma. The authors' in-depth analysis emphasizes Salbutamol's consistent efficacy over time, even as new bronchodilatory agents emerge. This finding provides valuable insight for clinicians, reinforcing Salbutamol's position as a trusted and effective treatment option. The authors also point to the potential for further research into the applications of Salbutamol in other areas, such as premature labor, hyperkalemia, and cardiac failure.

Salbutamol: A Reliable Partner for Respiratory Health

The research emphasizes the importance of appropriate administration and dose management for Salbutamol to optimize therapeutic benefits and minimize potential side effects. The study encourages individuals with asthma to work closely with their healthcare providers to determine the most effective route of administration, as well as the appropriate dosage based on their individual needs. It's always important to remember that while Salbutamol is generally well-tolerated, it's crucial to be aware of potential side effects and report any unusual symptoms to a doctor immediately.

Dr. Camel's Conclusion

This research is like a soothing oasis in the vast desert of respiratory ailments. Salbutamol's proven efficacy and safety over the years, akin to the enduring strength of a camel traversing the desert, make it a reliable companion for individuals with asthma. However, as with any journey through the desert, it's essential to be mindful of potential challenges and seek guidance when needed. This research serves as a valuable reminder that while new discoveries may arise, some solutions remain timeless and effective.

Date :
  1. Date Completed 1989-09-27
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

2670512

DOI: Digital Object Identifier

10.2165/00003495-198938010-00004

Related Literature

SNS
PICO Info
in preparation
Languages

English

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