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Tricyclic and related drugs for nocturnal enuresis in children.

Author: CaldwellPatrina H Y, SureshkumarPremala, WongWicky C F

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Tricyclics are effective at reducing the number of wet nights during treatment, but do not have a sustained effect after treatment stops. Alarm therapy has better short- and long-term outcomes. Tricyclics combined with anticholinergics may be more effective that tricyclic monotherapy.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Enuresis (bedwetting) affects up to 20% of five year-olds and 2% of adults. Although spontaneous remission often occurs, the social, emotional and psychological costs can be great. Tricyclics have been used to treat enuresis since the 1960s. OBJECTIVES: To assess the effects of tricycli...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741207/

データ提供：米国国立医学図書館（NLM）

Treating Nocturnal Enuresis in Children: A Comprehensive Review of Tricyclic Drugs

Nocturnal enuresis, or bedwetting, is a common childhood problem that can have significant social and emotional impacts. This review examines the use of tricyclic antidepressants for treating nocturnal enuresis in children, comparing their effectiveness with other interventions. Think of this review as a comprehensive guide for parents navigating the desert of bedwetting treatment options, seeking the most effective and safe solution for their children.

Tricyclic Antidepressants: A Promising Treatment for Bedwetting

This review suggests that tricyclic antidepressants, particularly imipramine, can be effective in reducing the number of wet nights in children with nocturnal enuresis. However, the authors emphasize the need for further research to clarify the long-term effectiveness of these medications and to explore the potential risks and benefits for individual children. It's important to note that tricyclic antidepressants are not a first-line treatment for bedwetting, and other interventions, such as alarms, may be more effective in some cases.

Understanding the Treatment Options for Bedwetting

This review provides valuable information for parents and healthcare professionals seeking to manage nocturnal enuresis in children. It highlights the different treatment options available, including tricyclic antidepressants, alarms, and behavioral therapies. By understanding the relative effectiveness and potential side effects of each option, parents can make informed decisions about the best approach for their child.

Dr. Camel's Conclusion

This review provides a thorough exploration of tricyclic antidepressants as a treatment for nocturnal enuresis. It's a reminder that the search for effective treatments for childhood conditions is a complex journey, and while tricyclic antidepressants may offer a promising path for some children, they are not a one-size-fits-all solution. As with any medical treatment, careful consideration of individual needs and risks is essential.

Date :
  1. Date Completed 2016-05-10
  2. Date Revised 2023-11-08
Further Info :

Pubmed ID

26789925

DOI: Digital Object Identifier

PMC8741207

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