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Full-thickness porcine burns infected with Staphylococcus aureus or Pseudomonas aeruginosa can be effectively treated with topical antibiotics.
Author: CatersonE J, ErikssonElof, HacklFlorian, JunkerJohan P E, KiwanukaElizabeth, LeeCameron C Y, MinasianRaquel A, OnderdonkAndrew, TracyLauren E, TsaiDavid M
Original Abstract of the Article :
Burn and blast injuries are frequently complicated by invasive infections, which lead to poor wound healing, delay in treatment, disability, or death. Traditional approach centers on early debridement, fluid resuscitation, and adjunct intravenous antibiotics. These modalities often prove inadequate ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://doi.org/10.1111/wrr.12409
データ提供:米国国立医学図書館(NLM)
Topical Antibiotics for Infected Burns
Burn injuries are often complicated by infections, which can hinder healing and lead to serious complications. This study explored the effectiveness of topical antibiotics in treating infected burns in a porcine model. The researchers investigated the use of high concentrations of gentamicin and minocycline applied directly to the burn wounds.
Topical Antibiotics Show Effectiveness
The results showed that topical application of high concentrations of gentamicin and minocycline significantly reduced bacterial counts in infected full-thickness porcine burns. This approach proved effective against both Staphylococcus aureus and Pseudomonas aeruginosa infections, the two most common bacteria associated with burn wound infections.
Promising Approach to Burn Wound Management
This study suggests that topical delivery of ultrahigh concentrations of antibiotics could be a promising approach to treating infected burns. It offers a potential alternative to traditional methods, such as systemic antibiotics, which may be less effective in reaching the burn wound due to compromised local vasculature.
Dr.Camel's Conclusion
Like a camel's ability to adapt to harsh desert conditions, this study highlights the potential of topical antibiotics in adapting to the challenges of burn wound management. This approach could significantly improve the healing process and reduce the risk of infection, offering a valuable tool for burn care.
Date :
- Date Completed 2018-04-11
- Date Revised 2018-04-19
Further Info :
Related Literature
English
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