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Intermittent BRAF Inhibition Can Achieve Prolonged Disease Control in BRAF Mutant Melanoma.
Author: BryceAlan, JainTania
Original Abstract of the Article :
BRAF V600E is the most common somatic mutation seen in patients with metastatic melanoma. BRAF inhibitors (BRAFi), along with MEK inhibitors (MEKi), have been shown to improve overall survival in these patients with a median time to resistance of 6-10 months. We describe a patient with an ongoing re...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725676/
データ提供:米国国立医学図書館(NLM)
Intermittent BRAF Inhibition Can Achieve Prolonged Disease Control in BRAF Mutant Melanoma
Imagine melanoma as a treacherous desert, a challenging environment for those who venture there. This research, published in 2016, explores the possibility of using intermittent therapy with BRAF inhibitors, drugs that target a specific mutation in the BRAF gene, to manage BRAF mutant melanoma. This approach aims to control the disease while minimizing the side effects associated with continuous treatment.
Intermittent Therapy - A New Approach to Cancer Treatment
The study describes a patient who achieved a remarkable 48-month response with intermittent BRAF inhibitor therapy. It's like a wise desert traveler, using strategic pauses to conserve energy and resources during a long journey. The researchers suggest that this approach could provide a way to control melanoma for extended periods while reducing the burden of side effects on patients.
Managing Cancer - Balancing Treatment and Quality of Life
This research opens new possibilities for managing melanoma, highlighting the value of personalized medicine and finding the right balance between treatment and quality of life. It's a reminder that, just as a camel must adapt its pace and rest periods to the demands of the desert, we need to find a rhythm that works for each individual in the fight against cancer. This research is a beacon of hope, showing that we can navigate the challenges of cancer with greater control and flexibility.
Dr.Camel's Conclusion
This research offers a fresh perspective on cancer treatment, demonstrating the potential of intermittent therapy to provide lasting disease control while minimizing side effects. It's a testament to the ingenuity of medical research and the ongoing quest to improve the lives of cancer patients. It's a journey of discovery, just like a camel's trek across the vast desert, leading us to new and promising horizons.
Date :
- Date Completed 2016-01-29
- Date Revised 2020-09-30
Further Info :
Related Literature
English
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