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Oral pharmacotherapy for overactive bladder in older patients: mirabegron as a potential alternative to antimuscarinics.

Author: BernerTodd, Castro-DiazDavid, KelleherCon, NittiVictor W, SiddiquiEmad, WaggAdrian

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
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ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Mirabegron, a β3-adrenergic receptor agonist, offers a different tolerability profile compared to antimuscarinics for treating overactive bladder in older adults, minimizing the risk of anticholinergic burden.
Paper Details　
Original Abstract of the Article :
Overactive bladder (OAB) is a particular challenge to treat in older adults with co-morbid conditions taking multiple medications. Antimuscarinics (e.g., solifenacin, fesoterodine) and β3-adrenergic receptor agonists (mirabegron) are similarly efficacious; however, antimuscarinics may be associated ...See full text at original site
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引用元：
https://doi.org/10.1185/03007995.2016.1149806

データ提供：米国国立医学図書館（NLM）

Mirabegron: A Potential Oasis in the Desert of Overactive Bladder

Overactive bladder (OAB) can significantly impact an individual's quality of life, especially for older adults who often face multiple health challenges. This study, like a seasoned desert explorer, investigates the potential of mirabegron, a β3-adrenergic receptor agonist, as a treatment option for OAB. The researchers compared the efficacy and tolerability of mirabegron to traditional antimuscarinics, seeking to identify a safer and more effective treatment approach.

Navigating the Desert of OAB: Exploring New Treatment Avenues

The study highlights the potential of mirabegron as a viable alternative to antimuscarinics in treating OAB, particularly in older adults. Mirabegron's unique mechanism of action and distinct tolerability profile make it a promising option, offering potential benefits for individuals with OAB and multiple co-morbidities.

Finding Relief in the Desert of OAB: Considerations for Healthcare Professionals

This study provides valuable insights for healthcare professionals treating OAB, particularly in older adults. The findings suggest that mirabegron could offer a safer and more effective alternative to antimuscarinics, especially for individuals taking multiple medications. Healthcare providers should carefully consider mirabegron as a potential treatment option for OAB, balancing its efficacy with its tolerability profile and minimizing anticholinergic burden.

Dr. Camel's Conclusion

The desert of OAB can be a challenging and uncomfortable landscape, but this study offers hope for individuals seeking relief. Mirabegron, with its unique properties and potential for improved tolerability, may provide a valuable oasis in the desert of OAB treatment. Healthcare professionals should carefully consider mirabegron as a potential treatment option, particularly for older adults with OAB and multiple co-morbidities, striving to optimize patient care and improve their overall well-being.

Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26828974

DOI: Digital Object Identifier

10.1185/03007995.2016.1149806

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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