Paper Details
- Home
- Paper Details
Enhancement of solubility and antidiabetic effects of Repaglinide using spray drying technique in STZ-induced diabetic rats.
Author: AhmadiMahdieh, GhassamiErfaneh, MinayianMohsen, VarshosazJaleh
Original Abstract of the Article :
The purpose of the study was to enhance the solubility of the poorly water-soluble drug, Repaglinide using spray drying based solid dispersion technique by different carriers including Eudragit E100, hydroxyl propyl cellulose Mw 80 000 and poly vinyl pyrollidone K30. Optimization of the best formula...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.3109/10837450.2016.1143001
データ提供:米国国立医学図書館(NLM)
Boosting Repaglinide's Effectiveness: Enhancing Solubility for Improved Diabetes Management
Diabetes is a chronic condition that affects millions worldwide. This study focuses on improving the effectiveness of repaglinide, a medication used to treat type 2 diabetes. The researchers investigated the use of spray drying, a technique that can enhance the solubility of poorly water-soluble drugs like repaglinide.
Spray Drying: A Solution for Poorly Soluble Drugs
Spray drying involves converting a liquid solution into a fine powder, increasing the drug's surface area and improving its solubility. It's like creating a miniature desert oasis, where the drug can dissolve more easily and be absorbed more effectively. This study explored the use of spray drying to enhance the solubility of repaglinide, potentially leading to better blood sugar control for diabetes patients.
Improving Diabetes Management: Enhancing Drug Delivery
This research suggests that spray drying can significantly improve the solubility and effectiveness of repaglinide. It's like finding a hidden well in the desert of diabetes treatment, offering a more efficient way to deliver this essential medication. However, further research is needed to fully understand the long-term effects and optimize the use of spray-dried repaglinide in diabetes management.
Dr.Camel's Conclusion
This study highlights the potential of spray drying as a powerful tool for improving drug delivery and effectiveness. This innovative approach could revolutionize diabetes treatment, offering patients a more effective and efficient way to manage their blood sugar levels. It's like discovering a new oasis in the vast desert of diabetes research, providing hope for a brighter future for those living with this condition.
Date :
- Date Completed 2018-05-09
- Date Revised 2018-12-02
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.