Paper Details 
Original Abstract of the Article :
The purpose of the study was to enhance the solubility of the poorly water-soluble drug, Repaglinide using spray drying based solid dispersion technique by different carriers including Eudragit E100, hydroxyl propyl cellulose Mw 80 000 and poly vinyl pyrollidone K30. Optimization of the best formula...See full text at original site
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引用元:
https://doi.org/10.3109/10837450.2016.1143001

データ提供:米国国立医学図書館(NLM)

Boosting Repaglinide's Effectiveness: Enhancing Solubility for Improved Diabetes Management

Diabetes is a chronic condition that affects millions worldwide. This study focuses on improving the effectiveness of repaglinide, a medication used to treat type 2 diabetes. The researchers investigated the use of spray drying, a technique that can enhance the solubility of poorly water-soluble drugs like repaglinide.

Spray Drying: A Solution for Poorly Soluble Drugs

Spray drying involves converting a liquid solution into a fine powder, increasing the drug's surface area and improving its solubility. It's like creating a miniature desert oasis, where the drug can dissolve more easily and be absorbed more effectively. This study explored the use of spray drying to enhance the solubility of repaglinide, potentially leading to better blood sugar control for diabetes patients.

Improving Diabetes Management: Enhancing Drug Delivery

This research suggests that spray drying can significantly improve the solubility and effectiveness of repaglinide. It's like finding a hidden well in the desert of diabetes treatment, offering a more efficient way to deliver this essential medication. However, further research is needed to fully understand the long-term effects and optimize the use of spray-dried repaglinide in diabetes management.

Dr.Camel's Conclusion

This study highlights the potential of spray drying as a powerful tool for improving drug delivery and effectiveness. This innovative approach could revolutionize diabetes treatment, offering patients a more effective and efficient way to manage their blood sugar levels. It's like discovering a new oasis in the vast desert of diabetes research, providing hope for a brighter future for those living with this condition.

Date :
  1. Date Completed 2018-05-09
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26895041

DOI: Digital Object Identifier

10.3109/10837450.2016.1143001

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Languages

English

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