Paper Details

  1. Home
  2. Paper Details

Effects of vildagliptin versus saxagliptin on daily acute glucose fluctuations in Chinese patients with T2DM inadequately controlled with a combination of metformin and sulfonylurea.

Author: JingWang, ShunyouDeng, XiaochunHuang, XiaoyanChen, YingyuFu, YuyuTan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study compared the effects of vildagliptin and saxagliptin, dipeptidyl peptidase-4 (DPP-4) inhibitors, on 24-hour acute glucose fluctuations in Chinese patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and sulfonylurea. Vildagliptin showed a significantly greater reduction in acute glucose fluctuations compared to saxagliptin, suggesting a potential benefit in managing T2DM.
Paper Details　
Original Abstract of the Article :
Objective The present study aimed to compare the effects of the dipeptidyl peptidase-4 (DPP-4) inhibitors vildagliptin and saxagliptin on 24 hour acute glucose fluctuations in Chinese patients with type 2 diabetes mellitus (T2DM) inadequately controlled with a combination of metformin and sulfonylur...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1185/03007995.2016.1162773

データ提供：米国国立医学図書館（NLM）

Vildagliptin: A New Path for Managing Blood Sugar Fluctuations

Type 2 diabetes mellitus (T2DM) is a chronic condition that affects millions worldwide. This study investigates the effects of vildagliptin and saxagliptin, two DPP-4 inhibitors, on daily blood sugar fluctuations in patients with T2DM who are inadequately controlled with conventional medications. This research explores the nuances of DPP-4 inhibitors in managing blood sugar fluctuations, offering potential advantages for patients with T2DM.

Vildagliptin's Superiority in Managing Blood Sugar Fluctuations

The study found that vildagliptin produced a significantly greater reduction in acute glucose fluctuations compared to saxagliptin. This finding suggests that vildagliptin may be a more effective option for managing blood sugar fluctuations in patients with T2DM.

Navigating the Desert of Blood Sugar Control

This research highlights the importance of finding the right treatment for individuals with T2DM. Vildagliptin's superior ability to manage blood sugar fluctuations is a valuable insight into the complexities of diabetes management.

Dr.Camel's Conclusion

Vildagliptin's effectiveness in reducing blood sugar fluctuations is a beacon of hope in the desert of diabetes research. This research encourages further exploration of DPP-4 inhibitors for effective diabetes management.

Date :
  1. Date Completed 2017-09-12
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

26950829

DOI: Digital Object Identifier

10.1185/03007995.2016.1162773

Related Literature

Article Analysis
・Effects of saxagliptin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.