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Associations among Erythroferrone and Biomarkers of Erythropoiesis and Iron Metabolism, and Treatment with Long-Term Erythropoiesis-Stimulating Agents in Patients on Hemodialysis.

Author: HiraoKeiichi, HondaHirokazu, KobayashiYasuna, OnumaShoko, ShibagakiKeigo, ShibataTakanori, TomosugiNaohisa, YamamotoToshinori, YuzaToshitaka

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the relationship between erythroferrone (ERFE), a regulator of hepcidin, and biomarkers of erythropoiesis and iron metabolism. The study also examined the effects of erythropoiesis-stimulating agents on ERFE production in patients on hemodialysis.
Paper Details　
Original Abstract of the Article :
We aimed to identify associations between erythroferrone (ERFE), a regulator of hepcidin 25, and biomarkers of erythropoiesis and iron metabolism. We also aimed to determine the effects of erythropoiesis-stimulating agents (ESA), continuous erythropoietin receptor activator (CERA) and darbepoetin-α ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792384/

データ提供：米国国立医学図書館（NLM）

Erythroferrone: A Key Player in Iron Regulation and Erythropoiesis

Iron is a vital mineral, playing a crucial role in oxygen transport and overall health. This study investigates the role of erythroferrone (ERFE), a hormone involved in iron regulation, in patients on hemodialysis. The researchers analyze the relationship between ERFE levels and various biomarkers of erythropoiesis and iron metabolism, exploring the complex interplay of these factors in hemodialysis patients.

Erythroferrone: A New Understanding of Iron Regulation in Hemodialysis

This research provides valuable insights into the role of ERFE in iron regulation and erythropoiesis in hemodialysis patients. The study highlights the complex relationship between ERFE and other biomarkers, underscoring the importance of understanding this interplay for optimizing iron management in these patients.

Erythroferrone: Optimizing Iron Management in Hemodialysis Patients

This research underscores the importance of considering ERFE levels when managing iron in hemodialysis patients. The study's findings offer potential for developing new strategies for optimizing iron management and improving overall health outcomes in these patients.

Dr.Camel's Conclusion

Just as a camel navigates the vast and unpredictable desert, this research explores the intricate pathways of iron regulation in hemodialysis patients. Erythroferrone emerges as a crucial player in this complex process, offering a new understanding of iron management and potential avenues for improving health outcomes.

Date :
  1. Date Completed 2016-07-26
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

26978524

DOI: Digital Object Identifier

PMC4792384

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Languages

English

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