Novel epigenetic-based therapies useful in cardiovascular medicine.

Author: De PascaleMaria Rosaria, GrimaldiVincenzo, InfanteTeresa, NapoliClaudio, SommeseLinda, SoricelliAndrea

Paper Details 
Original Abstract of the Article :
Epigenetic modifications include DNA methylation, histone modifications, and microRNA. Gene alterations have been found to be associated with cardiovascular diseases, and epigenetic mechanisms are continuously being studied to find new useful strategies for the clinical management of afflicted patie...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766271/

データ提供:米国国立医学図書館(NLM)

Epigenetics: Unlocking the Secrets of Cardiovascular Health

Cardiovascular diseases (CVDs), a leading cause of death worldwide, are complex and multifaceted. Epigenetics, the study of heritable changes in gene expression without alterations to the underlying DNA sequence, has emerged as a promising field for understanding and treating CVDs. This review delves into the role of epigenetic modifications, including DNA methylation, histone modifications, and microRNAs, in CVDs. The authors discuss the potential of targeting these epigenetic mechanisms for therapeutic intervention, highlighting emerging therapies that could revolutionize the management of CVDs. The review examines the current status of research and development in this field, identifying both promising opportunities and remaining challenges.

Epigenetic Therapies: A New Frontier in CVD Management

The review highlights the potential of epigenetic therapies for treating CVDs. By targeting specific epigenetic mechanisms, these therapies aim to modulate gene expression and restore cellular function, potentially preventing or reversing the progression of CVDs. It’s like discovering hidden pathways in a desert landscape, leading to new strategies for navigating and managing the complexities of CVDs.

A Promise for Personalized Medicine

Epigenetic therapies have the potential to usher in a new era of personalized medicine for CVDs. By tailoring treatments to the specific epigenetic profiles of individual patients, these therapies could offer more effective and targeted interventions, potentially improving outcomes and reducing side effects. It's like using a personalized compass to navigate the unique terrain of each individual's cardiovascular health, providing tailored solutions for optimal outcomes.

Dr. Camel's Conclusion

This review provides a comprehensive overview of the emerging role of epigenetics in cardiovascular disease. The research highlights the potential of targeting epigenetic modifications for therapeutic intervention, offering a promising new frontier in the management of CVDs. Epigenetic therapies hold great promise for personalized medicine, offering the potential for more effective and targeted treatments, potentially improving outcomes and enhancing the lives of individuals facing cardiovascular challenges.

Date :
  1. Date Completed 2016-03-16
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

26981216

DOI: Digital Object Identifier

PMC4766271

Related Literature

SNS
PICO Info
in preparation
Languages

English

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