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Aminophylline and caffeine for reversal of adverse symptoms associated with regadenoson SPECT MPI.

Author: DoranJesse A, GuptaRohit, MackinMaria L, SajjadWaseem, SchneiderMarabel D, SchwartzRonald G

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Retracted PublicationCases where a publication has been formally withdrawn due to the discovery of serious errors or misconduct.

Overview

Intravenous aminophylline and IV caffeine provide rapid, safe reversal of regadenoson-induced adverse effects during SPECT MPI. Oral caffeine appeared similarly effective for complete reversal but not for the combined complete and predominant reversal.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Aminophylline shortages led us to compare intravenous (IV) aminophylline with IV and oral (PO) caffeine during routine pharmacologic stress testing with SPECT MPI. METHODS: We measured presence, duration, and reversal of adverse symptoms and cardiac events following regadenoson administ...See full text at original site
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引用元：
https://doi.org/10.1007/s12350-016-0452-0

データ提供：米国国立医学図書館（NLM）

Reversing the Effects of a Desert Storm: Finding Relief from Regadenoson

Imagine a desert where a sudden sandstorm has blown in, causing discomfort and disruption. This research focuses on the effects of a medication called regadenoson, which is used to stress the heart during medical imaging. It's like a planned sandstorm, created to reveal hidden patterns in the landscape of the heart.

Navigating the After-Effects

The problem is that regadenoson can sometimes cause unpleasant side effects, like a lingering discomfort after the sandstorm has passed. This study explores different ways to reverse these effects, like finding a way to soothe the desert after the storm has subsided.

A Trio of Solutions for Relief

The researchers tested three different medications: aminophylline, caffeine, and oral caffeine. These medications are like different methods for calming the desert after the sandstorm, each with its own strengths and weaknesses. They found that all three medications were effective in reversing the side effects of regadenoson, but aminophylline and IV caffeine were slightly faster and more effective.

Dr. Camel's Conclusion

This research provides valuable insights into managing the side effects of regadenoson. By understanding different methods for reversing these effects, we can ensure a smoother and more comfortable experience for patients undergoing this procedure. It's like having a variety of tools in our toolkit, allowing us to tackle the challenges of the desert with greater ease and expertise.
Date :
  1. Date Completed 2018-03-26
  2. Date Revised 2023-10-10
Further Info :

Pubmed ID

27025843

DOI: Digital Object Identifier

10.1007/s12350-016-0452-0

Related Literature

Article Analysis
・Side Effects of aminophylline
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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