A Comparison between the Effects of Albendazole and Mebendazole on the Enzymatic Activity of Excretory / Secretory Products of Echinococcus granulosus Protoscoleces in Vitro.

Author: Adnani SadatiSeyed Jafar, EshraghiyanMohammad Reza, FarahnakAli, GolestaniAbolfazl, Molaei RadMohammad Bagher

Paper Details 
Original Abstract of the Article :
Hydatid cysts are formed in human body can be treated clinically by surgery or drugs such as albendazole (ABZ) and mebendazole (MBZ). The purpose of this study was comparing the effects of ABZ and MBZ on glutathione-S-transferase, alkaline phosphatase and protease enzymes activities in protoscoleces...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841877/

データ提供:米国国立医学図書館(NLM)

The Effects of Albendazole and Mebendazole on Echinococcus granulosus Protoscoleces

This study delves into the fascinating world of parasites and their impact on the human body. It explores the effectiveness of two commonly used medications, albendazole (ABZ) and mebendazole (MBZ), in combating a parasitic infection known as hydatid cyst disease. The study utilized a laboratory setting, examining the effect of these drugs on the enzymatic activity of crucial components of the parasite, Echinococcus granulosus protoscoleces. This is like studying how different pesticides affect specific parts of a bug to see which one is the most effective in controlling its growth and spread. The researchers observed that ABZ and MBZ had significant effects on the activity of certain enzymes within the parasite, suggesting their potential as therapeutic agents for the treatment of hydatid cyst disease.

A Promising Solution for Hydatid Cyst Disease

This research provides valuable insights into the potential of ABZ and MBZ in treating hydatid cyst disease. Their impact on the enzymatic activity of the parasite suggests a promising therapeutic approach. The results of this study could pave the way for future research exploring the optimal dosage and administration of these drugs for effective treatment.

Keep Hydatid Cyst Disease in Mind

This study reminds us of the importance of understanding parasitic infections and their potential to affect human health. It highlights the need for further research and development of effective treatments for these diseases, particularly those with significant public health implications. The study also emphasizes the critical role of appropriate hygiene practices and preventative measures in minimizing the risk of parasitic infections.

Dr.Camel's Conclusion

The study investigates the effectiveness of albendazole and mebendazole in inhibiting the enzymatic activity of Echinococcus granulosus protoscoleces. While this is a promising approach, further research is needed to fully understand the impact of these medications on the parasite and to develop effective treatment strategies for hydatid cyst disease.
Date :
  1. Date Completed 2016-04-26
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27114987

DOI: Digital Object Identifier

PMC4841877

Related Literature

SNS
PICO Info
in preparation
Languages

English

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