Paper Details 
Original Abstract of the Article :
Fingolimod, a first-in-class sphingosine 1-phosphate receptor modulator, is the first approved oral therapy for relapsing multiple sclerosis (MS). While treatment initiation of clinical dose of fingolimod (0.5 mg) does not affect pulmonary function, supra-therapeutic doses (≥5.0 mg) increased airway...See full text at original site
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引用元:
https://doi.org/10.1002/cpdd.4

データ提供:米国国立医学図書館(NLM)

Fingolimod: A Potential New Treatment for Moderate Asthma?

This study investigates the tolerability and pulmonary pharmacodynamic effects of fingolimod, a sphingosine 1-phosphate receptor modulator, in patients with moderate asthma. The research explores the potential for fingolimod, a medication primarily used for multiple sclerosis, to be a safe and effective treatment option for moderate asthma. The study found that fingolimod at the standard therapeutic dose (0.5 mg) was well-tolerated and did not significantly affect pulmonary function in patients with moderate asthma. However, higher doses of fingolimod were associated with a mild reduction in lung function and an increase in rescue bronchodilator use. This research provides valuable insights into the potential use of fingolimod for managing asthma, highlighting its potential benefits and risks.

Fingolimod: A Promising Avenue for Asthma Treatment?

This study, like a desert traveler venturing into a new oasis, explores the potential of fingolimod as a novel treatment option for moderate asthma. The study's findings suggest that fingolimod may be a safe and well-tolerated treatment option for moderate asthma at the standard therapeutic dose. However, the researchers also note that higher doses can lead to negative effects on lung function. This research highlights the importance of careful dose titration and monitoring for potential side effects.

Navigating the Complexities of Asthma Treatment: A Multifaceted Approach

This study encourages a multifaceted approach to managing asthma, considering the potential benefits and risks of new therapeutic options. The findings suggest that fingolimod may be a viable treatment option for certain patients with moderate asthma. However, it also highlights the importance of individualizing treatment plans based on patient factors and carefully monitoring for potential side effects. The study’s findings encourage further research to explore the full potential of fingolimod in managing asthma and develop more effective and safer treatments for this common condition.

Dr.Camel's Conclusion

This study provides valuable insights into the potential use of fingolimod for managing asthma. It's a reminder that as we continue to explore new therapeutic avenues, we must carefully weigh the potential benefits and risks of each treatment option and personalize care to meet the unique needs of individual patients. Like a camel navigating a complex desert ecosystem, we must be mindful of the interplay of various factors and strive for the best possible outcomes.

Date :
  1. Date Completed 2016-04-29
  2. Date Revised 2016-04-28
Further Info :

Pubmed ID

27121555

DOI: Digital Object Identifier

10.1002/cpdd.4

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Languages

English

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