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PO-55 - Individual variation in hemostatic alterations caused by tyrosine kinase inhibitors - a way to improve personalized cancer therapy?
Author: BoknäsN, DebS, LotfiK, RamströmS, SjöströmC, TharmakulanathanA
Original Abstract of the Article :
During the last two decades, Bcr-Abl tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myelogenous leukemia (CML), and are now considered standard treatment for this disease. However, TKIs can induce serious hemostatic side effects including cardiovascular disease and bl...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/S0049-3848(16)30188-8
データ提供:米国国立医学図書館(NLM)
Hemostatic Alterations and Tyrosine Kinase Inhibitors: A Personalized Approach to CML Treatment
Chronic myelogenous leukemia (CML), a type of blood cancer, is like a relentless desert storm, disrupting the normal flow of life. Tyrosine kinase inhibitors (TKIs), a class of medications used to treat CML, act like a powerful wind, pushing back against the storm. This study, like a careful observation of the storm's dynamics, investigates the effects of TKIs on hemostasis, the body's blood clotting process.
The researchers, like meteorologists studying the storm, explore the complex interplay between TKIs and platelet aggregation. They emphasize the need for a deeper understanding of how different TKIs affect hemostasis to minimize the risk of bleeding complications in patients.
Individualized Treatment: Navigating the Storm with Precision
This study, like a detailed map of the storm, highlights the importance of individualized treatment in CML management. By understanding the unique effects of different TKIs on hemostasis, doctors can personalize treatment plans to minimize the risk of bleeding complications.
A Balancing Act: Effective Treatment and Minimal Risk
The desert of CML requires a careful balance between effective treatment and minimal risk. This study, like a skilled camel rider navigating the shifting sands, emphasizes the need for individualized treatment strategies to ensure that patients receive the most effective therapy while minimizing the risk of bleeding complications.
Dr.Camel's Conclusion
The desert of CML can be a challenging landscape, but with a personalized approach to treatment, we can navigate the storm and guide patients toward a safer and healthier future. This study underscores the importance of understanding the unique effects of TKIs on hemostasis to minimize risks and maximize patient well-being.
Date :
- Date Completed 2016-06-10
- Date Revised 2016-05-10
Further Info :
Related Literature
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