Paper Details 
Original Abstract of the Article :
Guanfacine extended release (GXR) and atomoxetine (ATX) are nonstimulant treatments for attention-deficit/hyperactivity disorder (ADHD). As nonstimulant treatments are often used after stimulants in ADHD, GXR was assessed relative to prior stimulant treatment in a randomized controlled trial (RCT), ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863687/

データ提供:米国国立医学図書館(NLM)

Guanfacine Extended Release for ADHD: A Camel's Perspective

This research, a journey through the vast desert of attention-deficit/hyperactivity disorder (ADHD), focuses on exploring the effectiveness of guanfacine extended release (GXR) as a treatment for ADHD, particularly in those who have previously received stimulant medication. Like a camel navigating a sandstorm, researchers employed randomized controlled trials (RCTs) and randomized-withdrawal studies (RWSs) to map the efficacy of GXR. This study aimed to unearth the effectiveness of GXR compared to other nonstimulant treatments like atomoxetine (ATX), and especially in individuals who have already ventured into the world of stimulant medications, such as methylphenidate (MPH). The study's findings reveal that GXR holds its ground, proving effective regardless of previous stimulant treatment, much like a camel carrying its burdens across unforgiving landscapes. However, ATX appears to be less effective in those who have previously experienced stimulants, a reminder that the paths of treatment are not always straightforward.

GXR: A Beacon of Hope for ADHD Treatment?

The study unveils a significant finding: GXR, much like a dependable oasis in the desert, provides relief for ADHD symptoms, even in those who have tried and perhaps even failed with stimulants. This discovery has important implications for how we navigate the treatment landscape for ADHD, especially in situations where stimulants have not been effective.

Navigating the ADHD Treatment Desert

This research reminds us that, like the desert, the journey through ADHD treatment is unpredictable. Just as a camel may need to adapt its approach to different terrains, individuals with ADHD may require different treatments as their needs evolve. It is essential to collaborate with your doctor, like a wise guide leading you through the dunes, to find the most effective and personalized treatment strategy.

Dr. Camel's Conclusion

The study's findings about the effectiveness of GXR in ADHD patients, even those who have previously tried stimulants, offer a glimmer of hope in the vast desert of ADHD treatment. This research is an important step in understanding the diverse needs of patients and finding more effective treatment options. As a seasoned researcher with a love for the desert, I am reminded that even in the most challenging environments, there is always hope and the possibility for discovery.
Date :
  1. Date Completed 2016-05-26
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

27226715

DOI: Digital Object Identifier

PMC4863687

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.