Molindone: effects in pigeons responding under conditional discrimination tasks.

Author: BerensK, ClearyJ P, DykstraL A, OlivetoA H, PickerM J

Paper Details 
Original Abstract of the Article :
Pigeons were trained to respond under three conditional discrimination procedures; 1) a fixed-consecutive-number procedure with (FCN 8-SD) and without (FCN 8) an added external discriminative stimulus, 2) a delayed matching-to-sample (DMTS) procedure using 0-sec, 2-sec and 8-sec delay intervals, and...See full text at original site
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引用元:
https://doi.org/10.1016/0091-3057(89)90176-7

データ提供:米国国立医学図書館(NLM)

Molindone: Effects in Pigeons Responding Under Conditional Discrimination Tasks

The study of animal behavior, much like navigating a vast desert, can lead to surprising discoveries. This study explores the effects of [molindone], an atypical neuroleptic agent, on the behavior of pigeons trained to perform various [conditional discrimination tasks]. Using a series of well-defined behavioral tests, researchers investigated how molindone influences the pigeons’ ability to learn and perform these tasks.

The study found that molindone impaired the pigeons’ performance on tasks that required them to remember and discriminate between stimuli. The researchers observed that molindone decreased accuracy on tasks involving [fixed-consecutive-number procedures] and [delayed matching-to-sample procedures]. Notably, the effects of molindone were more pronounced on tasks with longer delay intervals. The study also found that molindone decreased accuracy on tasks involving [repeated acquisition of behavioral chains], suggesting that it may disrupt the learning and performance of complex behavioral sequences.

Understanding the Effects of Molindone on Behavior

The study’s findings provide valuable insights into the behavioral effects of molindone. By studying the drug’s effects on pigeons performing specific behavioral tasks, the researchers gained a better understanding of how molindone influences cognitive processes. The results of this study could inform future research on the use of molindone in treating various behavioral disorders.

Implications for Understanding Neuroleptic Drugs

This study highlights the importance of using a variety of behavioral assays when studying the effects of neuroleptic drugs. By employing a comprehensive approach, researchers can gain a more complete understanding of the drug’s actions on the brain and behavior.

Dr.Camel's Conclusion

This study offers a fascinating glimpse into the effects of molindone on animal behavior. By observing the pigeons’ performance on various tasks, researchers were able to map the influence of molindone on cognitive processes. This study emphasizes the importance of using diverse behavioral assays to study neuroleptic drugs. Just as a traveler in the desert must adapt to the changing landscape, researchers must use diverse methods to understand the complex effects of medications on the brain and behavior.

Date :
  1. Date Completed 1989-07-12
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

2727003

DOI: Digital Object Identifier

10.1016/0091-3057(89)90176-7

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English

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