Evaluation of the Effects of Pasireotide LAR Administration on Lymphocele Prevention after Axillary Node Dissection for Breast Cancer: Results of a Randomized Non-Comparative Phase 2 Study.

Author: Boutmy-DeslandesEmmanuelle, BézuCorinne, ChéreauElisabeth, DaraïEmile, GarbayJean-Rémi, MazouniChafika, RouzierRoman, UzanCatherine, ZoharSarah

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The aim of this study was to assess the efficacy (response rate centered on 80%) of a somatostatin analog with high affinity for 4 somatostatin receptors in reducing the postoperative incidence of symptomatic lymphocele formation following total mastectomy with axillary lymph node dissect...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900597/

データ提供:米国国立医学図書館(NLM)

Evaluation of the Effects of Pasireotide LAR Administration on Lymphocele Prevention after Axillary Node Dissection for Breast Cancer

Lymphocele, a fluid collection that can occur after axillary node dissection, can cause discomfort and complications for breast cancer patients. This study explores the potential of pasireotide LAR, a somatostatin analog, to prevent post-operative lymphocele formation. The authors conducted a randomized controlled trial, comparing pasireotide LAR to placebo, in patients undergoing mastectomy and axillary node dissection. Their findings indicate that while pasireotide LAR showed a trend towards reducing lymphocele incidence, it did not achieve the desired response rate. This research suggests that pre-operative pasireotide LAR administration may not be the optimal approach to prevent post-operative lymphocele, highlighting the need for further investigation into alternative strategies.

Navigating the Complexities of Lymphocele Prevention

This research, like a camel traversing a complex and ever-changing desert landscape, sheds light on the complexities of preventing lymphocele formation. The findings, like a hidden oasis of knowledge, provide valuable insights into the efficacy of pasireotide LAR for this purpose, but also underscore the need for further exploration of alternative strategies.

The Pursuit of Optimal Solutions

The study encourages continued research into the prevention of lymphocele, like a tireless caravan seeking a safe passage through a challenging desert environment. This ongoing pursuit of optimal solutions, guided by scientific inquiry, is crucial for improving the care and well-being of breast cancer patients.

Dr. Camel's Conclusion

This research, like a camel venturing into the vast desert of breast cancer treatment, provides valuable insights into the potential of pasireotide LAR to prevent lymphocele formation. While the findings, like a shimmering mirage, may not offer a definitive solution, they encourage continued exploration of alternative strategies to improve the post-operative care of breast cancer patients.

Date :
  1. Date Completed 2017-07-27
  2. Date Revised 2019-02-13
Further Info :

Pubmed ID

27280398

DOI: Digital Object Identifier

PMC4900597

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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