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Brain Tissues Oxidative Damage as A Possible Mechanism of Deleterious Effects of Propylthiouracil- Induced Hypothyroidism on Learning and Memory in Neonatal and Juvenile Growth in Rats.
Author: BeheshtiFarimah, DastgheibSamaneh Sadat, FarrokhiEsmaeil, HadjzadehMousa Al-Reza, HosseiniMahmoud, VafaeeFarzaneh
Original Abstract of the Article :
The role of brain tissues oxidative damage in learning and memory impairments has been well documented. It is also well known that thyroid hormones have a critical role for the brain functions. The purpose of this study was to investigate the role of brain tissues oxidative damage as a possible mech...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656934/
データ提供:米国国立医学図書館(NLM)
Hypothyroidism: A Brain-Draining Desert for Learning and Memory
Hypothyroidism, a condition where the thyroid gland doesn't produce enough hormones, can have detrimental effects on brain function, particularly in young animals. This study investigates the impact of hypothyroidism on learning and memory in rats, It's like observing a young camel navigating the desert, with the lack of thyroid hormones creating a harsh environment that hampers its ability to learn and remember.
Oxidative Damage: A Brain-Draining Storm
The study reveals that hypothyroidism can lead to oxidative damage in brain tissues, disrupting the delicate balance of brain function. This is like a sandstorm sweeping through the desert, damaging the oasis and hindering the camel's ability to thrive.
Protecting the Brain: A Vital Role for Thyroid Hormones
This research underscores the importance of thyroid hormones for brain development and function. It's like ensuring that the oasis has access to the vital resources it needs to thrive, allowing the young camel to learn and grow effectively. The study highlights the need for early diagnosis and treatment of hypothyroidism to prevent potential brain damage and support optimal cognitive development.
Dr.Camel's Conclusion
This research reveals the crucial role of thyroid hormones in maintaining brain health, particularly in young animals. It's like ensuring that the oasis has access to the essential resources it needs to flourish, allowing the young camel to navigate the desert of life successfully. Understanding the impact of hypothyroidism on brain function can help us develop strategies for preventing cognitive impairment and ensuring optimal brain development.
Date :
- Date Completed 2016-06-10
- Date Revised 2020-10-01
Further Info :
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English
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