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Effects of Pitavastatin on Lipid Profiles in HIV-Infected Patients with Dyslipidemia and Receiving Atazanavir/Ritonavir: A Randomized, Double-Blind, Crossover Study.
Author: KiertiburanakulSasisopin, NumthavejPawin, PuangpetchApichaya, SukasemChonlaphat, ThakkinstianAmmarin, WongprikornAsita
Original Abstract of the Article :
BACKGROUND: Dyslipidemia as a risk factor of cardiovascular disease is common especially in HIV-infected patients who are using protease inhibitors (PIs) including atazanavir. Pitavastatin has less drug-drug interactions and demonstrable efficacy in decreasing lipid levels in non HIV-infected indivi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909195/
データ提供:米国国立医学図書館(NLM)
Pitavastatin: A Lipid-Lowering Journey for HIV-Infected Patients
This study examines the effectiveness of pitavastatin, a statin medication, in lowering lipid levels in HIV-infected patients with dyslipidemia who are receiving atazanavir/ritonavir, a protease inhibitor commonly used in HIV treatment. The research found that pitavastatin significantly reduced total cholesterol and low-density lipoprotein (LDL) levels in these patients, without significant hepatotoxicity or elevation in creatine phosphokinase levels. This study highlights the potential of pitavastatin as a safe and effective lipid-lowering agent for HIV-infected patients experiencing dyslipidemia.
Pitavastatin: A Lipid-Lowering Oasis in the Desert of HIV
This study offers a promising solution for HIV-infected patients struggling with dyslipidemia. Imagine a camel caravan traversing a desert, facing the challenges of dehydration and extreme temperatures. Pitavastatin acts as a refreshing oasis, providing relief from the burden of elevated lipid levels.
Navigating the Complexities of HIV Treatment
This research underscores the importance of managing lipid levels in HIV-infected patients, particularly those receiving protease inhibitors. It's like a camel caravan carefully navigating a desert with treacherous terrain. A well-chosen strategy, like the use of pitavastatin, can help ensure a safer and smoother journey towards better health.
Dr.Camel's Conclusion
This study investigates the effectiveness of pitavastatin in lowering lipid levels in HIV-infected patients, suggesting its potential as a safe and effective lipid-lowering agent for this population.
Date :
- Date Completed 2017-07-24
- Date Revised 2019-02-13
Further Info :
Related Literature
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