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Oral atenolol therapy for proliferating infantile hemangioma: A prospective study.
Author: ChenSiyuan, JiYi, JiangXiaoping, LiYuan, WangQi, XiangBo, XuZhicheng, YangXiaodong, ZhongLin
Original Abstract of the Article :
Propranolol, a lipophilic nonselective β-blocker, has recently been reported to be the treatment of choice for select types of infantile hemangiomas (IHs). Atenolol is a hydrophilic, selective β1-blocker and therefore may be not associated with side effects attributable to β2-adrenergic receptor blo...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998480/
データ提供:米国国立医学図書館(NLM)
A New Approach to Treating Infantile Hemangiomas
[Infantile hemangiomas (IHs)] are a common concern for parents and pediatricians. This study explores the [efficacy and safety] of [atenolol] as a treatment option for [proliferating IHs], a condition characterized by rapid growth. The researchers conducted a [prospective study] involving [76 infants] with [superficial or mixed IHs]. They administered [oral atenolol] in a [progressive schedule] to a maximum dose of [1 mg/kg per day] and monitored the [Hemangioma Activity Score (HAS)] to assess the effectiveness of the treatment.
Promising Results for Hemangioma Treatment
The study found that [atenolol] effectively [stopped the growth of IHs] in [93.4% of patients] within the first four weeks of treatment. The treatment also demonstrated significant [decreases in HAS scores] and led to an [excellent treatment response] in a substantial number of patients. Furthermore, the study found that [atenolol] was [safe] with [no significant adverse events] reported.
A Gentle Approach to Treatment
Just as a camel navigates the desert with a steady and measured pace, atenolol offers a gentler approach to treating IHs. This research underscores the importance of [individualized treatment plans] that take into consideration the specific needs of each patient. It emphasizes the need for [further research] to fully understand the long-term effects of atenolol.
Dr. Camel's Conclusion
This study provides encouraging evidence for the effectiveness and safety of atenolol in treating proliferating IHs. It offers a promising alternative treatment option for parents and pediatricians. Further research is warranted to explore the long-term effects and to optimize treatment protocols for this condition.
Date :
- Date Completed 2017-02-02
- Date Revised 2021-01-09
Further Info :
Related Literature
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