Paper Details 
Original Abstract of the Article :
Rotigotine transdermal patch (Leganto(®), Neupro(®)) is indicated for the treatment of restless legs syndrome (RLS); this article reviews the pharmacological properties of rotigotine transdermal patch and its clinical efficacy and tolerability in patients with RLS. The transdermal patch allows for a...See full text at original site
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引用元:
https://doi.org/10.1007/s40265-016-0601-4

データ提供:米国国立医学図書館(NLM)

A Transdermal Patch for Restless Legs Syndrome: A New Frontier

Restless legs syndrome (RLS) is a condition that can make falling asleep feel like trying to sleep on a bed of hot coals. This research explores the use of a transdermal patch containing rotigotine, a medication that mimics the function of dopamine, a neurotransmitter that plays a crucial role in regulating movement and sleep. The researchers, like skilled artisans, meticulously crafted this patch to deliver a continuous and stable release of rotigotine, bypassing the first-pass metabolism in the liver and allowing for consistent stimulation of dopamine receptors. Their research, like a well-worn path in the desert, reveals the effectiveness of this new treatment approach.

A New Oasis in RLS Management: Improved Efficacy and Tolerability

The study found that rotigotine transdermal patches, especially at higher dosages, led to significantly greater improvement in RLS symptoms compared to placebo. The continuous delivery of rotigotine, like a steady stream of water in the desert, provided sustained relief for up to five years. Importantly, the patch was generally well-tolerated, offering a promising alternative to other treatments with potentially more severe side effects.

Finding Relief in the Desert: Hope for RLS Sufferers

This research offers hope for those suffering from RLS, providing a new treatment option with improved efficacy and tolerability. The transdermal patch, like a portable oasis, allows for convenient and consistent medication delivery, potentially improving the quality of life for countless individuals.

Dr.Camel's Conclusion

Rotigotine transdermal patches represent a significant step forward in the management of restless legs syndrome. Like a camel navigating a treacherous desert, this new treatment approach offers a sustained and well-tolerated path towards relief for those suffering from this debilitating condition.

Date :
  1. Date Completed 2017-03-23
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27324269

DOI: Digital Object Identifier

10.1007/s40265-016-0601-4

Related Literature

SNS
PICO Info
in preparation
Languages

English

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