Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi - a systematic review and economic evaluation.

Author: DarkPaul, Martyn-St JamesMarrissa, McMullanRonan, PandorAbdullah, PerkinsGavin D, RafiaRachid, SandersonJean, StevensJohn, StevensonMatt, UttleyLesley, WongRuth

Paper Details 
Original Abstract of the Article :
BACKGROUND: Sepsis can lead to multiple organ failure and death. Timely and appropriate treatment can reduce in-hospital mortality and morbidity. OBJECTIVES: To determine the clinical effectiveness and cost-effectiveness of three tests [LightCycler SeptiFast Test MGRADE(®) (Roche Diagnostics, Risch...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939418/

データ提供:米国国立医学図書館(NLM)

Navigating the Shifting Sands of Sepsis

The desert of sepsis, a life-threatening condition, can be unforgiving. This research focuses on the critical need for early and accurate diagnosis of bloodstream infections, which often mark the onset of sepsis. The researchers, like experienced navigators, aim to guide clinicians towards rapid identification of these dangerous invaders, akin to spotting a mirage in the desert, providing a crucial lifeline.

They embark on a systematic review and economic evaluation of three different tests, comparing their effectiveness against traditional blood cultures. The findings, like a well-mapped route, suggest that while these tests may offer advantages in identifying the culprit bacteria or fungi, their impact on patient outcomes remains uncertain. This emphasizes the need for further research, akin to searching for a hidden oasis that provides lasting relief.

The authors meticulously analyze the strengths and limitations of each test, highlighting the need for robust clinical trials to definitively establish their effectiveness. It's like searching for a reliable source of water in a vast and unforgiving desert, where every step requires caution and meticulous planning.

The Search for a Reliable Oasis

The researchers emphasize the importance of finding a reliable test for sepsis, a challenge akin to discovering a hidden oasis in the vast desert of medical complexities. While the tests studied may offer potential advantages, their effectiveness in improving patient outcomes remains elusive, requiring further exploration and research.

Staying Hydrated in the Desert

Sepsis, like a harsh desert environment, can quickly turn fatal. This research underscores the crucial need for swift and accurate diagnosis, emphasizing the importance of consulting with healthcare professionals immediately if experiencing symptoms of sepsis. Remember, early detection and treatment, like finding a life-saving oasis, can make a significant difference in navigating the treacherous path of this disease.

Dr. Camel's Conclusion

The quest for a reliable oasis in the desert of sepsis continues. This research, like a carefully curated map, provides valuable insights into the challenges and opportunities for early detection and treatment of this dangerous condition. Further research, like exploring a vast and unknown territory, is crucial for finding a lasting solution.

Date :
  1. Date Completed 2018-02-12
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27355222

DOI: Digital Object Identifier

PMC4939418

SNS
PICO Info
in preparation
Languages

English

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