Paper Details 
Original Abstract of the Article :
Clinical guidelines continue to move away from routine prostate specific antigen screening (PSA), once a widespread medical practice. A curious difference exists between early prostate cancer and early breast cancer. While randomized trials of therapy in early breast cancer continue to show overall ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.mehy.2016.05.019

データ提供:米国国立医学図書館(NLM)

Is Prostate Cancer Screening Responsible for the Negative Results of Prostate Cancer Treatment Trials?

The field of [prostate cancer treatment] is riddled with complexities, and the role of [prostate specific antigen (PSA) screening] has become a subject of intense debate. This research examines the puzzling discrepancy between the positive outcomes of [early breast cancer treatment] trials and the lack of clear benefits seen in [prostate cancer treatment] trials. It's like comparing two deserts – one where the oases are well-defined and easy to find, and another where the oases are obscured by a vast expanse of sand.

The author proposes that [prostate cancer screening] may be contributing to the negative results of [prostate cancer treatment trials] by leading to [overdiagnosis], where non-life-threatening cancers are detected and treated unnecessarily. This can blur the lines between true and false positives, making it difficult to assess the true effectiveness of treatments. It's like finding a small mirage in the desert, mistaking it for a real oasis, and then expending resources unnecessarily.

The Need for Rethinking Screening Practices

The research suggests that [prostate cancer screening] may need to be reevaluated, particularly in the context of [treatment trials]. It's important to ensure that we're not treating non-life-threatening cancers, which can skew the results of clinical trials. It's like carefully evaluating the oases we discover in the desert – ensuring they are genuine sources of water and not merely mirages.

The Quest for Effective Prostate Cancer Treatment

The quest for effective [prostate cancer treatment] continues, and this research highlights the importance of considering the potential impact of [screening practices]. It's like carefully mapping the desert landscape, identifying the true oases and avoiding the false ones, to ensure the most effective and targeted treatments for patients.

Dr.Camel's Conclusion

This research raises important questions about the impact of [prostate cancer screening] on the effectiveness of treatment trials. It's crucial to ensure that we're targeting the right cancers and avoiding unnecessary treatments. It's like using a compass to navigate the desert – ensuring we're heading in the right direction and avoiding dead ends.

Date :
  1. Date Completed 2017-06-15
  2. Date Revised 2017-06-15
Further Info :

Pubmed ID

27372859

DOI: Digital Object Identifier

10.1016/j.mehy.2016.05.019

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.