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A Safety and Efficacy Study of Tolvaptan Following Open Heart Surgery in 109 Cases.

Author: HoriHidetsugu, KonoTakanori, TanakaHiroyuki, TayamaEiki, UedaTomohiro, YamakiYuta

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Tolvaptan, a drug used to increase urine output, was found to be safe and effective in patients after open heart surgery. While no fatal adverse events were observed, rapid increases in serum sodium levels were seen in some patients, requiring close monitoring.
Paper Details　
Original Abstract of the Article :
This study was conducted to evaluate the safety and efficacy of tolvaptan following open heart surgery.We retrospectively reviewed 109 patients who were administered tolvaptan following open heart surgery between August 2011 and July 2014. We divided the patients according to their urine output inde...See full text at original site
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引用元：
https://doi.org/10.1536/ihj.15-483

データ提供：米国国立医学図書館（NLM）

Tolvaptan After Open Heart Surgery: A Safety and Efficacy Evaluation

The world of open heart surgery is a delicate one, with post-operative fluid management being a crucial aspect of patient care. This study examines the safety and efficacy of tolvaptan, a medication that promotes urine output, in patients recovering from open heart surgery. The researchers conducted a retrospective review of a cohort of patients who received tolvaptan after open heart surgery, meticulously analyzing data on urine output, serum sodium levels, and other clinical parameters.

Tolvaptan: A Safe and Effective Tool for Post-Operative Fluid Management

This study demonstrates the safety and efficacy of tolvaptan for increasing urine output in patients recovering from open heart surgery. The researchers found that tolvaptan effectively promoted urine production without significantly affecting blood pressure or renal function. The study also highlighted the importance of monitoring serum sodium levels to prevent rapid increases. This finding underscores the importance of careful observation and individualized management when using tolvaptan in post-operative patients.

A New Approach to Optimizing Recovery After Open Heart Surgery

This study offers valuable insights into post-operative fluid management after open heart surgery. The findings suggest that tolvaptan can be a safe and effective tool for promoting urine output, potentially aiding in patient recovery. Like a camel skillfully navigating the desert, healthcare providers must carefully consider individual patient needs and adjust treatment strategies accordingly to optimize patient outcomes.

Dr.Camel's Conclusion

This study provides a valuable assessment of tolvaptan's safety and efficacy in managing post-operative fluid balance after open heart surgery. The findings suggest that tolvaptan can be a useful tool for promoting urine output and potentially contributing to smoother recovery. Like a camel navigating a challenging terrain, healthcare providers must remain vigilant and adaptable in their approach to post-operative care.

Date :
  1. Date Completed 2017-03-07
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27396557

DOI: Digital Object Identifier

10.1536/ihj.15-483

Related Literature

Article Analysis
・Effects of tolvaptan (low blood sodium)
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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