FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs.

Author: BaiGe, BeaverJulia A, CharlabRosane, ChenXiao Hong, ChengJoyce, DininJeannette, DorffSarah E, IbrahimAmna, IsonGwynn, JinRunyan, KimGeoffrey, LiuQi, MaratheAnshu, McGuinnW David, McKeeAmy E, PalmbyTodd R, PazdurRichard, PierceWilliam, SridharaRajeshwari, StephensOlen, TangShenghui, WangYaning, YsernXavier

Paper Details 
Original Abstract of the Article :
On December 11, 2015, the FDA approved uridine triacetate (VISTOGARD; Wellstat Therapeutics Corporation) for the emergency treatment of adult and pediatric patients following a fluorouracil or capecitabine overdose regardless of the presence of symptoms, and of those who exhibit early-onset, severe,...See full text at original site
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引用元:
https://doi.org/10.1158/1078-0432.CCR-16-0638

データ提供:米国国立医学図書館(NLM)

Uridine Triacetate: A Lifeline in the Desert of Drug Overdose

Navigating the complexities of cancer treatment can be a daunting journey, and drug overdoses can be a treacherous desert storm. This study, like a beacon of hope in the midst of a crisis, explores the use of uridine triacetate (VISTOGARD) for the emergency treatment of fluorouracil or capecitabine overdose. The researchers, like skilled paramedics rushing to a scene, investigated the effectiveness of uridine triacetate in a real-world setting, analyzing data from over 135 patients.

Uridine Triacetate: A Potential Antidote for Drug Overdose

This research, like a desert oasis offering vital sustenance, highlights the potential of uridine triacetate as a life-saving treatment for fluorouracil or capecitabine overdose. The researchers found that uridine triacetate, like a carefully crafted antidote, was effective in preventing life-threatening complications and enabling patients to resume chemotherapy. This study, like a testament to the power of medical innovation, demonstrates the potential of uridine triacetate to provide a lifeline for patients experiencing drug overdose, offering a chance to navigate the treacherous terrain of cancer treatment with a greater chance of survival.

Navigating the Desert of Cancer Treatment: A Journey With Unexpected Challenges

This study, like a desert journey fraught with unexpected challenges, reveals the importance of ongoing research to further understand the risks and benefits of uridine triacetate. While the study highlights the potential benefits of uridine triacetate, it also emphasizes the need for careful monitoring of side effects and further investigation into its long-term effects. This study, like a well-worn path in the desert, serves as a guide for future research to navigate the complex landscape of cancer treatment and ensure the safety and efficacy of innovative therapies.

Dr.Camel's Conclusion

This study provides important evidence for the potential of uridine triacetate as a life-saving treatment for fluorouracil or capecitabine overdose. The findings highlight the need for further research to optimize its use and ensure its long-term safety and efficacy.

Date :
  1. Date Completed 2018-01-12
  2. Date Revised 2018-01-12
Further Info :

Pubmed ID

27401247

DOI: Digital Object Identifier

10.1158/1078-0432.CCR-16-0638

Related Literature

SNS
PICO Info
in preparation
Languages

English

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