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[Pharmacokinetic, bacteriological and clinical evaluation of sulbactam/ampicillin in pediatrics].

Author: HayashiM, KidaK, MatsudaH, MuraseM

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Sulbactam/ampicillin (SBT/ABPC) showed good pharmacokinetics, efficacy, and safety in children with various infections. It was effective against Staphylococcus aureus and Haemophilus influenzae but less effective against Escherichia coli.
Paper Details　
Original Abstract of the Article :
The pharmacokinetics, efficacy and safety of sulbactam/ampicillin (SBT/ABPC) were evaluated in 21 children with a variety of infections. The results obtained are summarized as follows. 1. Pharmacokinetics in 4 children, each receiving a single dose of 60 mg/kg, were evaluated. The average half-life ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2746854

データ提供：米国国立医学図書館（NLM）

Sulbactam/Ampicillin: A Journey Through Pediatric Infections

Sulbactam/ampicillin (SBT/ABPC), a common antibiotic combination, is like a desert nomad, traveling through the body to fight infections. This study explores the pharmacokinetics, efficacy, and safety of SBT/ABPC in pediatric patients, navigating the complexities of treating infections in young children.

The researchers meticulously evaluated the pharmacokinetics, efficacy, and safety of SBT/ABPC in a group of children with various infections. Their findings, like a carefully crafted map of the body's intricate pathways, revealed that SBT/ABPC was effective in treating a range of infections, with a high clinical efficacy rate and a favorable safety profile.

The study underscores the importance of carefully tailoring antibiotic treatment to individual patients, considering their age, weight, and specific infection. It's like choosing the best path through the desert, selecting the most appropriate route for a successful journey.

A Valuable Tool for Pediatric Infections

The study demonstrates the effectiveness of SBT/ABPC in treating a range of pediatric infections, offering a valuable option for clinicians.

Navigating Pediatric Infections

The research emphasizes the importance of careful and individualized antibiotic therapy in pediatric patients, highlighting the need to consider their unique needs and vulnerabilities.

Dr. Camel's Conclusion

Sulbactam/ampicillin is a valuable tool for treating pediatric infections, offering a safe and effective treatment option. This study provides important insights into the use of this antibiotic combination in young children, reminding us to always consider the individual patient and their specific needs.

Date :
  1. Date Completed 1989-08-18
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

2746854

DOI: Digital Object Identifier

2746854

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Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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