Paper Details 
Original Abstract of the Article :
Metastatic renal cell carcinoma (mRCC) develops in approximately 33% of all renal cancer patients. First line treatment of mRCC includes drugs such as sunitinib, temsirolimus and pazopanib, with overall survival now reaching up to 43,6months in patients with favorable-risk metastatic disease. Severa...See full text at original site
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引用元:
https://doi.org/10.1016/j.mehy.2016.07.015

データ提供:米国国立医学図書館(NLM)

Unveiling the Metabolic Secrets of Metastatic Renal Cancer

Metastatic renal cell carcinoma (mRCC) is a challenging disease, like a desert sandstorm that can quickly engulf the body. This study explores the metabolic changes that occur during the treatment of mRCC, seeking to understand how these changes can be used as potential biomarkers for treatment efficacy. The researchers embarked on a journey through the intricate landscape of mRCC, seeking to uncover the hidden clues of metabolic changes.

The study observed changes in lipid profiles, iron, and ferritin levels during mRCC treatment. The researchers hypothesize that these changes may be primarily caused by mTOR inhibition, a key pathway targeted by mRCC therapies. The study suggests that these metabolic changes may be correlated with treatment efficacy, potentially serving as biomarkers to monitor treatment response. This research sheds light on the complex metabolic landscape of mRCC, offering potential avenues for improving treatment strategies.

Metabolic Changes: A Window into mRCC Treatment

This study highlights the potential of metabolic changes, specifically in lipid profiles, iron, and ferritin levels, as potential biomarkers for monitoring treatment efficacy in mRCC. The researchers emphasize the importance of further research to validate these findings and explore their clinical implications. This research could lead to more personalized and effective treatment strategies for mRCC.

Navigating the Desert of mRCC Treatment

This study offers a valuable glimpse into the complex metabolic landscape of mRCC treatment. The researchers explore the potential of metabolic changes as biomarkers, providing a roadmap for further investigation and potentially leading to more effective treatment strategies.

Dr.Camel's Conclusion

The desert of mRCC can be a challenging journey for patients, but researchers are constantly seeking new paths to effective treatment. This study explores the potential of metabolic changes as biomarkers, potentially offering a more precise and personalized approach to mRCC treatment.

Date :
  1. Date Completed 2017-06-16
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

27515221

DOI: Digital Object Identifier

10.1016/j.mehy.2016.07.015

Related Literature

SNS
PICO Info
in preparation
Languages

English

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