Emerging Antiepileptic Drugs for Severe Pediatric Epilepsies.

Author: MudigoudarBasanagoud, WeatherspoonSarah, WhelessJames W

Paper Details 
Original Abstract of the Article :
The medical management of the epilepsy syndromes of early childhood (eg, infantile spasms, Dravet syndrome, and Lennox-Gastaut syndrome) is challenging; and requires careful evaluation, classification, and treatment. Pharmacologic therapy continues to be the mainstay of management for these children...See full text at original site
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引用元:
https://doi.org/10.1016/j.spen.2016.06.003

データ提供:米国国立医学図書館(NLM)

Pediatric Epilepsy: Emerging Treatments for Severe Seizures

This study delves into the [neurology] realm and discusses the challenges of managing severe pediatric epilepsy syndromes, such as infantile spasms, Dravet syndrome, and Lennox-Gastaut syndrome. The study focuses on the role of newly approved antiepileptic drugs, including vigabatrin, rufinamide, perampanel, and clobazam, as well as those in clinical trials, such as cannabidiol, stiripentol, and fenfluramine. The study emphasizes the increasing role of genetic research in identifying specific developmental and seizure disorders that may be treatable with targeted drug therapies. The study concludes by highlighting the potential for precision medicine in the future, with therapies tailored to individual genetic profiles.

New Hope for Pediatric Epilepsy: Emerging Treatments

The study's findings highlight the progress made in treating severe pediatric epilepsies, with the development of new antiepileptic drugs and the potential for personalized therapies based on genetic insights. These advancements offer hope for children with epilepsy and their families, providing a greater range of treatment options and the potential for improved outcomes.

A Brighter Future: Pediatric Epilepsy and Precision Medicine

Pediatric epilepsy is a complex and challenging condition. This research underscores the importance of continued research and innovation in developing effective and safe therapies for children with epilepsy. The potential for precision medicine, tailoring treatments to individual genetic profiles, offers a promising path towards more personalized and effective care, improving the lives of children with epilepsy and their families.

Dr.Camel's Conclusion

Epilepsy can be a daunting desert, but with the emergence of new treatments and the promise of precision medicine, we can hope for a brighter future for children with this condition.

Date :
  1. Date Completed 2018-01-26
  2. Date Revised 2018-02-22
Further Info :

Pubmed ID

27544474

DOI: Digital Object Identifier

10.1016/j.spen.2016.06.003

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