Impacts of 12-dose regimen for latent tuberculosis infection: Treatment completion rate and cost-effectiveness in Taiwan.

Author: HuangYi-Wen, TsaoShih-Ming, TsaoThomas Chang-Yao, YangShun-Fa, YehYen-Po

Paper Details 
Original Abstract of the Article :
Treatment of latent tuberculosis infection (LTBI) is essential for eradicating tuberculosis (TB). Moreover, the patient adherence is crucial in determining the effectiveness of TB control. Isoniazid given by DOTS daily for 9 months (9H) is the standard treatment for LTBI in Taiwan. However, the comp...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400306/

データ提供:米国国立医学図書館(NLM)

Latent Tuberculosis Infection: A Short-Term Treatment Approach

Tuberculosis (TB), a disease that has plagued humanity for centuries, continues to pose a significant threat. Latent TB infection (LTBI), where the bacteria are present but not actively causing disease, is a crucial focus for TB control. This study compares two treatment regimens for LTBI: the standard 9-month isoniazid regimen (9H) and the 12-week rifapentine/isoniazid regimen (3HP). The researchers conducted a pilot study to assess the treatment completion rates and costs of these two regimens. The study found that the 3HP regimen resulted in a significantly higher treatment completion rate compared to the 9H regimen. Moreover, the 3HP regimen proved to be more cost-effective, with a lower cost per case of tuberculosis avoided.

A More Efficient Approach: The 3HP Regimen Shows Promise

This study's findings suggest that the 3HP regimen could be a more effective and cost-effective approach to treating LTBI. The 3HP regimen's shorter duration and higher completion rate could lead to better patient adherence and potentially reduce the spread of TB. Think of it like a camel traversing a desert, a shorter and more efficient route can lead to a faster and more successful journey.

Improving Treatment Outcomes: A Step Towards TB Control

The study's findings provide valuable information for TB control strategies. The 3HP regimen's higher completion rate and cost-effectiveness could contribute to more effective TB management. However, further research is needed to confirm these findings in larger populations and explore the long-term implications of this treatment regimen.

Dr.Camel's Conclusion

This study suggests that the 3HP regimen could be a more effective and cost-effective approach to treating LTBI. This could lead to better patient adherence and potentially reduce the spread of TB.

Date :
  1. Date Completed 2017-02-08
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

27559940

DOI: Digital Object Identifier

PMC5400306

Related Literature

SNS
PICO Info
in preparation
Languages

English

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