Opioid-Induced Androgen Deficiency (OPIAD): Diagnosis, Management, and Literature Review.

Author: O'RourkeTimothy K, WosnitzerMatthew S

Paper Details 
Original Abstract of the Article :
Opioid-induced androgen deficiency (OPIAD) was initially recognized as a possible consequence of opioid use roughly four decades ago. Long-acting opioid use carries risks of addiction, tolerance, and systemic side effects including hypogonadotropic hypogonadism with consequent testosterone depletion...See full text at original site
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引用元:
https://doi.org/10.1007/s11934-016-0634-y

データ提供:米国国立医学図書館(NLM)

Opioid-Induced Androgen Deficiency (OPIAD): A Hidden Consequence of Opioid Use

Opioid use can have far-reaching effects, impacting not only the central nervous system but also hormone levels. This study explores the phenomenon of opioid-induced androgen deficiency (OPIAD), a condition characterized by low testosterone levels due to long-term opioid use. The researchers provide an overview of the pathophysiology, diagnosis, and management of OPIAD, including the potential benefits of testosterone replacement therapy (TRT) and clomiphene citrate, a selective estrogen receptor modulator (SERM), in addressing this condition.

OPIAD: Unveiling the Hidden Costs of Opioid Use

This study highlights the potential long-term consequences of opioid use, including OPIAD. The findings emphasize the need for comprehensive monitoring and management of hormone levels in patients on long-term opioid therapy. This is particularly important considering the potential impact of OPIAD on various aspects of health and well-being, such as sexual function, bone health, and mood.

Navigating the Opioid Landscape: Understanding OPIAD

Picture a camel traversing the desert, facing the challenges of dehydration and exhaustion. Long-term opioid use can be like a relentless desert heat, impacting various aspects of the body, including hormone levels. Understanding OPIAD is crucial for patients on opioid therapy, allowing them to work with their healthcare providers to address potential risks and manage their health proactively. It's essential to have open conversations about any changes in health, including potential hormonal imbalances, to ensure timely and appropriate treatment.

Dr.Camel's Conclusion

This study sheds light on the complex effects of opioid use, reminding us that the journey of recovery can be challenging and require comprehensive care. OPIAD, like a hidden oasis, requires a deep understanding and careful management. By working closely with healthcare professionals and seeking appropriate treatment options, individuals can navigate the complexities of opioid use and work towards a healthier and more balanced life.

Date :
  1. Date Completed 2016-12-15
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27586511

DOI: Digital Object Identifier

10.1007/s11934-016-0634-y

Related Literature

SNS
PICO Info
in preparation
Languages

English

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