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Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma.

Author: DelebinskiCatharina I, EggertAngelika, JägerSebastian, KleinsimonSusann, RolffJana, SeifertGeorg, TwardziokMonika

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Ewing sarcoma is a type of bone cancer that affects children and adolescents. A combination of mistletoe extracts has shown to be an effective treatment for this cancer. This therapy works by triggering apoptosis in the cancerous cells.
Paper Details　
Original Abstract of the Article :
Ewing sarcoma is the second most common bone cancer in children and adolescents, with poor prognosis and outcome in ~70% of initial diagnoses and 10-15% of relapses. Hydrophobic triterpene acids and hydrophilic lectins and viscotoxins from European mistletoe (Viscum album L.) demonstrate anticancer ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010293/

データ提供：米国国立医学図書館（NLM）

Combating Ewing Sarcoma: A Multi-pronged Approach Inspired by Mistletoe

The field of [Ewing sarcoma], a type of [bone cancer], is facing the formidable challenge of finding effective treatments. This study delves into the potential of [Viscum album L. (European mistletoe)] extracts, a natural remedy, to combat this aggressive cancer. Researchers investigated the effects of both [hydrophobic triterpene acids] and [hydrophilic lectins and viscotoxins] derived from [Viscum album L.] on [Ewing sarcoma] cells. The study revealed that combining these extracts generated a synergistic effect, like combining the strength of different desert plants to create a robust defense against harsh conditions. They discovered that this combination treatment induced [apoptosis] in [Ewing sarcoma] cells, effectively halting the cancer's growth. This is like finding a potent natural poison that can kill off a deadly desert scorpion.

Mistletoe Extracts: A Promising Weapon in the Fight Against Ewing Sarcoma

The study suggests that [Viscum album L. extracts] could offer a novel and natural approach to treating [Ewing sarcoma]. This is like discovering a hidden oasis in the desert, offering a source of healing and rejuvenation. Further research is needed to fully understand its efficacy and determine the optimal dosage and treatment regimen.

Seeking Natural Solutions: A Reminder for Patients and Clinicians

This research highlights the importance of exploring [natural remedies] for treating [cancer], drawing on the wisdom of traditional medicine and the vast diversity of the natural world. The desert is rich in untapped resources, offering a wealth of potential solutions to the challenges we face.

Dr. Camel's Conclusion

This study provides a promising glimpse into the potential of [Viscum album L.] extracts to combat [Ewing sarcoma]. By harnessing the power of nature, we can continue to explore new pathways for treating this devastating disease.

Date :
  1. Date Completed 2017-08-01
  2. Date Revised 2019-02-12
Further Info :

Pubmed ID

27589063

DOI: Digital Object Identifier

PMC5010293

Related Literature

Article Analysis
・Effective treatment of european mistletoe
SNS
PICO Info
in preparation
Languages

English

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