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Salvianolic acid A alleviates ischemic brain injury through the inhibition of inflammation and apoptosis and the promotion of neurogenesis in mice.

Author: ChernChang-Ming, ChienMei-Yin, ChuangCheng-Hung, HouYu-Chang, LiouKou-Tong, LiuDer-Zen, ShenYuh-Chiang

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Salvianolic acid A has been shown to protect against acute ischemic stroke in mice. It reduces inflammation and promotes neurogenesis, which leads to improved survival rate and reduced brain damage.
Paper Details　
Original Abstract of the Article :
Salvianolic acid A (SalA), a chemical type of caffeic acid trimer, has drawn great attention for its potent bioactivities against ischemia-induced injury both in vitro and in vivo. In this study, we evaluated SalA's protective effects against acute ischemic stroke by inducing middle cerebral artery ...See full text at original site
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引用元：
https://doi.org/10.1016/j.freeradbiomed.2016.09.006

データ提供：米国国立医学図書館（NLM）

Salvianolic Acid A: A Camel's Guide to Protecting the Brain

The brain is a delicate organ, vulnerable to the ravages of ischemia, a condition that occurs when blood flow to the brain is interrupted. This research explores the potential neuroprotective effects of salvianolic acid A, a natural compound derived from the Salvia miltiorrhiza plant. The authors investigate the effects of salvianolic acid A in mice with ischemic brain injury, examining its ability to reduce inflammation, apoptosis, and promote neurogenesis.

Salvianolic Acid A: A Beacon of Hope in the Desert of Ischemia

This study suggests that salvianolic acid A may offer a new avenue for protecting the brain from ischemic damage. It's like finding a hidden oasis in the desert of brain injury, providing a source of nourishment and renewal. The authors demonstrate the compound's ability to reduce inflammation, promote neurogenesis, and protect against cell death, highlighting its potential for mitigating the devastating effects of ischemia.

Protecting the Oasis: A Journey Towards Brain Health

This research underscores the importance of exploring natural compounds for treating brain injury. It's like seeking out hidden treasures in the vast desert of medicinal plants. Salvianolic acid A offers a promising path towards safeguarding the delicate oasis of brain health, offering a potential solution for a debilitating condition.

Dr. Camel's Conclusion

This study offers a glimmer of hope in the desert of ischemic brain injury. It's like finding a hidden spring in the arid landscape, offering a source of healing and renewal. Salvianolic acid A holds promise for protecting the brain and promoting recovery, providing a beacon of hope for those affected by ischemic brain injury.

Date :
  1. Date Completed 2018-01-02
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

27609227

DOI: Digital Object Identifier

10.1016/j.freeradbiomed.2016.09.006

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