Evaluation of an ultra-low-dose oral contraceptive for dysmenorrhea: a placebo-controlled, double-blind, randomized trial.

Author: HaradaTasuku, MomoedaMikio

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy and safety of an ultra-low-dose oral contraceptive (NPC-01; 0.02 mg ethinyl estradiol and 1 mg norethisterone) in subjects with dysmenorrhea. DESIGN: Placebo-controlled, double-blind, randomized trial. SETTING: Clinical trial sites. PATIENT(S): Two hundred fift...See full text at original site
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引用元:
https://doi.org/10.1016/j.fertnstert.2016.08.051

データ提供:米国国立医学図書館(NLM)

Ultra-Low-Dose Oral Contraceptive for Dysmenorrhea: A Promising Solution

Dysmenorrhea, painful periods, can be a debilitating condition for many women. This study explores the efficacy and safety of an ultra-low-dose oral contraceptive (NPC-01) in treating this condition. The researchers conducted a placebo-controlled, double-blind randomized trial comparing NPC-01 to a standard oral contraceptive (IKH-01) and a placebo. Their findings revealed that NPC-01 significantly reduced dysmenorrhea scores compared to the placebo, demonstrating its effectiveness in alleviating pain.

A Gentle Approach to Managing Dysmenorrhea

The results of this study suggest that NPC-01, with its ultra-low dose, offers an effective and potentially safer alternative for treating dysmenorrhea. The study highlights the importance of finding gentler treatment options for managing this condition, which can significantly impact a woman's quality of life. This research paves the way for exploring new approaches to managing menstrual pain with a focus on minimizing side effects.

Finding Relief from Menstrual Discomfort

This study offers hope for those seeking relief from dysmenorrhea. While NPC-01 showed effectiveness, it's important to note that it was associated with a higher incidence of side effects compared to the placebo. However, these side effects were similar to those experienced with the standard oral contraceptive, indicating a potentially manageable trade-off. This research underscores the importance of finding the right balance between effectiveness and safety when treating dysmenorrhea.

Dr. Camel's Conclusion

Imagine a desert where the scorching sun represents the pain of dysmenorrhea. NPC-01, like a refreshing oasis, provides potential relief for those suffering from this condition. While it might come with some side effects, like a few prickly desert plants, it offers a potentially gentler and more effective approach to managing menstrual discomfort.

Date :
  1. Date Completed 2017-06-07
  2. Date Revised 2017-06-07
Further Info :

Pubmed ID

27717552

DOI: Digital Object Identifier

10.1016/j.fertnstert.2016.08.051

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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