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Bendectin and human congenital malformations.

Author: KlebanoffM A, ShionoP H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Bendectin exposure during pregnancy was not associated with an increased overall rate of major malformations. Three malformations were statistically associated with Bendectin use, but this was likely due to chance and not causal, as two of them were also associated with vomiting in the absence of Bendectin.
Paper Details　
Original Abstract of the Article :
The relationship between Bendectin exposure during the first trimester of pregnancy and the occurrence of congenital malformations was prospectively studied in 31,564 newborns registered in the Northern California Kaiser Permanente Birth Defects Study. The odds ratio for any major malformation and B...See full text at original site
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引用元：
https://doi.org/10.1002/tera.1420400208

データ提供：米国国立医学図書館（NLM）

Bendectin and Congenital Malformations: A Closer Look

Bendectin, an anti-nausea medication, was once widely used during pregnancy. This study explores the potential link between Bendectin exposure during pregnancy and the occurrence of congenital malformations. The study analyzed data from 31,564 newborns registered in the Northern California Kaiser Permanente Birth Defects Study.

No Evidence of Increased Risk

This study found no overall increase in the rate of major malformations after exposure to Bendectin. The findings suggest that Bendectin is not associated with a general increase in congenital malformations.

Navigating the Complexities of Pregnancy

This study highlights the complexity of understanding the potential risks and benefits of medications during pregnancy. It emphasizes the importance of conducting thorough research and carefully evaluating potential associations between medications and birth defects. This is like navigating a challenging desert journey – understanding the potential pitfalls is essential for a safe and successful expedition.

Dr. Camel's Conclusion

Like a camel traversing a vast and unforgiving desert, this study delves into the complexities of pregnancy and the potential risks of medications. It reminds us of the importance of careful research and evidence-based decision-making to ensure the safety and well-being of both mother and child.

Date :
  1. Date Completed 1989-10-04
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

2772850

DOI: Digital Object Identifier

10.1002/tera.1420400208

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English

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