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An Evaluation on the Efficacy and Safety of Treatments for Attention Deficit Hyperactivity Disorder in Children and Adolescents: a Comparison of Multiple Treatments.

Author: GaoJie, HeShu, LiYing, WangQiwei, ZhangYan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Lisdexamfetamine dimesylate (LDX) and methylphenidate (MPH) are the most effective medications for attention deficit hyperactivity disorder (ADHD) in children and adolescents. LDX has a lower rate of adverse effects, while MPH has the lowest incidence of side effects. Atomoxetine (ATX) has a lower risk of withdrawal, but its efficacy may be lower than LDX and MPH.
Paper Details　
Original Abstract of the Article :
Attention deficit hyperactivity disorder (ADHD) is one of the most common neurobehavioral disorders. We carried out this comparison of multiple treatments based on sufficient data in attempt to evaluate the efficacy and safety of ADHD medication for children and adolescents. PubMed, Embase and the C...See full text at original site
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引用元：
https://doi.org/10.1007/s12035-016-0179-6

データ提供：米国国立医学図書館（NLM）

ADHD Treatments: Navigating the Desert of Choices

Attention deficit hyperactivity disorder (ADHD), like a restless desert wind, can disrupt attention and focus, making it difficult to navigate daily life. This study compares the efficacy and safety of multiple treatments for ADHD in children and adolescents, guiding us through the vast desert of available options. The authors conduct a comprehensive meta-analysis, akin to using a detailed map to compare different routes through the desert.

Comparing ADHD Treatments: Finding the Right Oasis

The meta-analysis found that lisdexamfetamine dimesylate (LDX) was the most effective treatment for ADHD, followed by methylphenidate (MPH). This is like finding two different oases in the desert, each offering unique benefits for hydration and sustenance. The authors also found that MPH had the lowest incidence rate of adverse effects, while atomoxetine (ATX) had the lowest incidence rate of withdrawals. This is like comparing the safety of different desert paths, considering factors like the presence of obstacles and the potential for danger.

A Desert Oasis for ADHD: Choosing the Right Path

This research provides valuable insights for clinicians and families seeking to manage ADHD, offering a comprehensive comparison of the efficacy and safety of different treatment options. The study highlights the importance of carefully considering the individual needs of each patient when choosing the most appropriate treatment approach, just as a traveler might choose a different path based on their own goals and abilities.

Dr.Camel's Conclusion

This study helps navigate the desert of ADHD treatment options, offering a comprehensive comparison of different medications based on their efficacy and safety. Choosing the right treatment for ADHD is like finding the optimal path through the desert, ensuring the best possible outcome for each individual.

Date :
  1. Date Completed 2019-05-23
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

27738872

DOI: Digital Object Identifier

10.1007/s12035-016-0179-6

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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