Parasympathomimetic drugs for dry mouth due to radiotherapy.

Author: SpivakovskySylvia, SpivakovskyYael

Paper Details 
Original Abstract of the Article :
Data sourcesCochrane Oral Health Group Trials Register, Cochrane Central Register of Controlled Trials, Medline, Embase and CINAHL databases. Reference lists of identified articles were checked and experts in the field and relevant pharmaceutical companies were contacted.Study selectionRandomised co...See full text at original site
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引用元:
https://doi.org/10.1038/sj.ebd.6401185

データ提供:米国国立医学図書館(NLM)

Parasympathomimetic Drugs for Dry Mouth: A Limited Option

This research examines the effectiveness of parasympathomimetic drugs, such as pilocarpine hydrochloride, in treating radiation-induced dry mouth (xerostomia). The study systematically reviewed existing research, but found limited evidence to support the widespread use of these drugs. While some studies suggest that pilocarpine might improve xerostomia symptoms in approximately half of patients, side effects were frequently reported and often led to treatment discontinuation. The authors conclude that there is limited evidence to support the use of parasympathomimetic drugs for radiation-induced xerostomia, and further research is needed to explore alternative treatments.

Limited Evidence for Parasympathomimetic Drugs

This research highlights the need for further research into effective treatments for radiation-induced dry mouth (xerostomia). While parasympathomimetic drugs, such as pilocarpine hydrochloride, have shown some promise, the study's findings suggest that their effectiveness is limited and their side effects can be problematic. More research is needed to explore alternative and more effective treatments for this common side effect of radiation therapy.

Finding Effective Treatments for Radiation-Induced Dry Mouth

This research underscores the need for innovative approaches to managing radiation-induced dry mouth (xerostomia). The study's findings suggest that parasympathomimetic drugs may not be the ideal solution for this common side effect of radiation therapy. Further research into alternative treatments, including non-pharmacological approaches, is crucial to improve the quality of life for patients experiencing xerostomia.

Dr.Camel's Conclusion

Just as a camel adapts to the arid desert, we must find ways to help patients adapt to the challenges of radiation-induced dry mouth. This research highlights the need for further exploration of effective treatments for this condition. The journey towards better care for xerostomia is ongoing, and we must continue to seek innovative solutions to alleviate the discomfort and improve the quality of life for those affected. Let's continue our quest through the desert of medical knowledge, seeking new and effective ways to manage this challenging condition.

Date :
  1. Date Completed 2016-12-22
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27767109

DOI: Digital Object Identifier

10.1038/sj.ebd.6401185

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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