Thermosensitive bioadhesive gels for the vaginal delivery of sildenafil citrate: in vitro characterization and clinical evaluation in women using clomiphene citrate for induction of ovulation.

Author: AbbasAhmed M, FetihGihan, SolimanGhareb M

Paper Details 
Original Abstract of the Article :
The objective of this study is to develop and characterize in situ thermosensitive gels for the vaginal administration of sildenafil as a potential treatment of endometrial thinning occurring as a result of using clomiphene citrate for ovulation induction in women with type II eugonadotrophic anovul...See full text at original site
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引用元:
https://doi.org/10.1080/03639045.2016.1254239

データ提供:米国国立医学図書館(NLM)

Thermosensitive Bioadhesive Gels: A Novel Approach for Vaginal Delivery of Sildenafil

Navigating the complex landscape of women's health, researchers are constantly seeking innovative solutions to address common challenges. This study explores a novel approach to delivering sildenafil, a medication known for its effects on erectile dysfunction, directly to the vagina. The researchers aim to create a thermosensitive gel formulation that would provide a more targeted and effective treatment for endometrial thinning, a condition that can affect women undergoing ovulation induction. This approach could potentially improve the efficacy and minimize the side effects associated with oral sildenafil, making it a more appealing option for women facing infertility.

Thermosensitive Gels: A Promising Solution for Endometrial Thinning

This study, akin to a carefully curated desert garden, provides a potential solution to a persistent challenge faced by women undergoing fertility treatment. By developing a thermosensitive gel for vaginal delivery of sildenafil, the researchers aim to address the issue of endometrial thinning, a common complication associated with certain fertility medications. This approach could potentially provide a more effective and targeted treatment option, leading to improved outcomes for women struggling with infertility.

Thermosensitive Gels: A Step Towards Personalized Treatment

The development of thermosensitive bioadhesive gels for vaginal delivery of sildenafil represents a significant step towards personalized treatment for women facing infertility. This innovative approach could potentially minimize side effects and improve the effectiveness of treatment, offering a more comfortable and efficient option for women undergoing ovulation induction. It's like discovering a new path in the desert, leading to a more personalized and effective approach to addressing women's health concerns.

Dr. Camel's Conclusion

This research presents a novel approach to delivering sildenafil directly to the vagina through the use of thermosensitive bioadhesive gels. This innovative method could offer a more targeted and effective treatment for endometrial thinning in women undergoing ovulation induction, potentially leading to improved outcomes and reduced side effects. It's like finding a hidden oasis in the arid landscape of fertility treatment, offering a new source of hope for women facing infertility challenges.

Date :
  1. Date Completed 2017-06-06
  2. Date Revised 2017-06-06
Further Info :

Pubmed ID

27783532

DOI: Digital Object Identifier

10.1080/03639045.2016.1254239

Related Literature

SNS
PICO Info
in preparation
Languages

English

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