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Effects of Safinamide on Pain in Fluctuating Parkinson's Disease Patients: A Post-Hoc Analysis.

Author: BaronePaolo, BonizzoniErminio, CattaneoCarlo, SardinaMarco

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Pain is a common non-motor symptom in Parkinson's Disease (PD). Safinamide, a new drug with dopaminergic and non-dopaminergic properties, is approved for treating fluctuating PD patients. Two 24-month studies demonstrated that safinamide has positive effects on both motor functions and quality of life in PD patients.
Paper Details　
Original Abstract of the Article :
Pain, a frequent non-motor symptom in Parkinson's Disease (PD), significantly impacts on quality of life. Safinamide is a new drug with dopaminergic and non-dopaminergic properties, approved in Europe as adjunct therapy to levodopa for the treatment of fluctuating PD patients. Results from two 24-mo...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302028/

データ提供：米国国立医学図書館（NLM）

Safinamide: A Beacon of Hope for Fluctuating Parkinson's Disease

Parkinson's disease is a complex neurological condition that can significantly impact quality of life. This study investigates the effects of safinamide, a new drug, on pain experienced by patients with fluctuating Parkinson's disease. It's like finding a new type of camel that can navigate the rough terrain of this disease, bringing relief and improved quality of life.

Safinamide Shows Promise

The results of two long-term studies demonstrated that safinamide positively impacted both motor functions and quality of life in patients with Parkinson's disease. It's like discovering a hidden oasis in the desert of suffering, a place where patients can find respite and renewed hope. These promising findings indicate that safinamide could play a significant role in managing this challenging condition.

The Potential for Improved Quality of Life

The research suggests that safinamide may provide relief from pain and improve overall well-being for individuals with Parkinson's disease. It's like finding a new way to travel through the desert, a journey made smoother and more comfortable. The potential benefits of this drug are truly exciting.

Dr. Camel's Conclusion

This study offers a ray of hope for those living with Parkinson's disease. It's a reminder that even in the most challenging circumstances, there's always the possibility of finding new solutions and improving quality of life. It's a journey worth taking, one that could lead to a brighter future for many.

Date :
  1. Date Completed 2017-11-09
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

27802242

DOI: Digital Object Identifier

PMC5302028

Related Literature

Article Analysis
・Effects of safinamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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